How everyday personal care chemicals and body weight affect breast cancer risk
Excessive Weight, Breast Cancer, and Endocrine Disrupting Chemicals (EDCs): Findings From Active Living After Cancer (ALAC) With Environmental Vitality
M.D. Anderson Cancer Center · NCT07137468
For breast cancer survivors and their family members in the Acres Homes neighborhood, this project will see if chemicals from personal care products are linked with body weight and will gather their knowledge and interest about environmental exposures.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | M.D. Anderson Cancer Center (other) |
| Locations | 1 site (Houston, Texas) |
| Trial ID | NCT07137468 on ClinicalTrials.gov |
What this trial studies
This observational project engages breast cancer survivors and their family members from the Acres Homes community, including past or current Active Living After Cancer (ALAC) participants. Thirty people will take part in focus groups and surveys to document knowledge and interest in exposures from personal care products, and participants will provide urine and silicone wristband samples to measure non-persistent endocrine-disrupting chemicals (EDCs). The cross-sectional analysis will compare measured EDC levels with participants' BMI to explore associations between chemical exposures and excessive weight. Findings will be used to design the ALAC with Environmental Vitality (ALAC-ENV) educational intervention and to support a larger randomized trial application.
Who should consider this trial
Good fit: Ideal participants are English-speaking adults (18+) who live in the Acres Homes neighborhood and are breast cancer survivors (current or former ALAC participants) or family members of a survivor, without metastatic disease.
Not a fit: People with metastatic breast cancer, those who do not live in Acres Homes, or those unable to communicate in English are not eligible and would not benefit from participation in this project.
Why it matters
Potential benefit: If successful, this work could inform tailored education and interventions to reduce harmful chemical exposures and address weight-related factors that may lower breast cancer risk in an under-resourced community.
How similar studies have performed: Previous research has linked endocrine-disrupting chemicals, obesity, and breast cancer risk, but using community-focused focus groups plus wristband and urine measures in this specific population is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Be a resident of Acres Home community 2. Be 18 years of age and older 3. Self-report a breast cancer diagnosis including subtypes OR be a family member of a survivor 4. If a breast cancer survivor: current or former participants of the ALAC program 5. Able to communicate in English Exclusion Criteria: 1. Self-report metastatic breast cancer diagnosis 2. Unable to communicate in English 3. Not a breast cancer survivor or family member of a survivor
Where this trial is running
Houston, Texas
- The University of Texas M. D. Anderson Cancer Center — Houston, Texas, United States (RECRUITING)
Study contacts
- Principal investigator: Dede Teteh-Brooks, DRPH — M.D. Anderson Cancer Center
- Study coordinator: Dede Teteh-Brooks, DRPH
- Email: dkteteh@mdanderson.org
- Phone: 713-563-3493
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Breast Cancer