Clinical trial Recruiting at 1 site Observational Ages 18 to 40

How different grades of chondromalacia patella affect static and dynamic balance

Official title: EFFECT OF GRADES OF CHONDROMALACIA ON STATIC AND DYNAMIC BALANCE: CROSS-SECTIONAL STUDY

Run by Cairo University · NCT07014787 · Data updated 2026-11-12

We will test whether different grades of chondromalacia patella change static and dynamic balance in adults aged 18 to 40.

Quick facts

Study typeObservational
Ages18 Years to 40 Years
SexAll
Enrollment100 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Giza)
StatusRecruiting
StartedNovember 5, 2024
Main results expectedMay 30, 2025
Study endsJune 15, 2025
Registry record updatedJune 11, 2025
Trial IDNCT07014787 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18–40 with MRI-confirmed unilateral or bilateral chondromalacia (grade I–IV), BMI 19.0–29.0, symptom duration over three months, and a positive patellar grind test.

Probably not a fit

Patients with rheumatoid or other inflammatory arthritis, vestibular or neurological disorders, recent intra-articular knee injections (within 3 months), prior knee replacement, or those outside the age/BMI ranges are unlikely to benefit from or qualify for this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will recruit 100 participants including 80 patients with MRI-confirmed chondromalacia patella (20 each for grades I–IV) and 20 healthy controls. Participants will undergo static and dynamic balance testing using the Biodex Balance System at the Faculty of Physical Therapy, Cairo University. Eligible patients are adults 18–40 years old with BMI 19.0–29.0, chronic symptoms for more than three months, and a positive patellar grind test, while those with inflammatory arthritis, vestibular or neurological disorders are excluded.

Why it matters

Potential benefit: If successful, the results could help tailor rehabilitation and fall-prevention strategies by identifying grade-specific balance deficits in people with chondromalacia.

How similar studies have gone: Previous work has reported balance impairments in people with knee osteoarthritis and patellofemoral pain, but using the Biodex to compare balance across specific chondromalacia grades is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ranged from 18 to 40 years old
2. groups include both males and females
3. Patients with Grade I, II, III and IV chondromalacia: Confirmation of diagnosis by MRI
4. BMI will be ranged from 19.0 to 29.0
5. Patients with Unilateral or bilateral chondromalacia.
6. Chronic cases for more than 3 months.
7. Positive sign of Knee pain according to patellar Grind Test

Exclusion Criteria:

1. patients have not undergone knee replacement.
2. patients have not done Intra-articular injection in the affected knee for the past 3 months.
3. Patients with rheumatoid arthritis or other inflammatory arthritis.
4. Patients with Vestibular disorders or neurological conditions.

Where it's running

  • Faculty of physical therapy Cairo University
    Giza, Egypt
    Recruiting

Study contacts

  • Principal investigator: Selwan Khaled Ayad, Teacher Assistant — Cairo University
  • Study coordinator: Selwan Khaled Ayad, teacher Assistant
  • Email: selwan_kayad@outlook.com
  • Phone: +201064709563

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.