How daytime, nighttime, and combined heat exposure affect healthy young adults' bodies

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, controlled crossover human exposure trial in Hefei will enroll about 50 healthy young adults to measure acute physiological and psychological responses to heat. Participants undergo three exposure conditions—nighttime heat (30°C, 23:00–07:00), daytime heat (32°C, 09:00–17:00), and combined day–night exposures—each compared with a thermoneutral 26°C condition with at least a three-day washout between sessions. The study will collect cardiovascular, respiratory, neurocognitive, and metabolic outcomes and explore underlying biological mechanisms. Randomized crossover sequencing ensures within-subject comparisons of the different temperature conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18-30;
* In good health, with no history of cardiovascular disease, respiratory disease, diabetes, endocrine disorders, neurological or psychiatric conditions;
* No smoking or alcohol addiction, no history of substance abuse;
* No prior history of particular sensitivity to high-temperature environments.

Exclusion Criteria:

* Individuals who have experienced fever, colds, infectious diseases, or significant physical trauma within two weeks prior to the high-temperature test;
* Individuals currently using medications that may affect psychological, cognitive, cardiovascular, or respiratory functions;
* Pregnant women and lactating females;
* Participants shall not be scheduled to participate during menstruation;
* Individuals with a history of fainting or severe discomfort caused by high temperatures.

Where it's running

• Anhui Medical University
  Hefei, Anhui, China Recruiting

Study contacts

• Study coordinator: Jian Jian Cheng
• Email: jiancheng@ahmu.edu.cn
• Phone: +86 183 5603 7837

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.