How controlled sounds and sensory stimulation affect the brain in an acoustic chamber
Official title: Exploration phénotypique en Contexte de Stimulations Sensorielles en Chambre Acoustique
Run by Centre Hospitalier St Anne · NCT07544563 · Data updated 2026-11-12
This project will test how controlled sensory stimulation, such as music, changes brain activity and behavior in adults with epilepsy and in healthy volunteers.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 320 (estimated) |
| Sponsor | Centre Hospitalier St Anne Academic / other |
| Locations | 1 site (Paris) |
| Status | Recruiting |
| Started | December 2, 2025 |
| Main results expected | December 2, 2035 |
| Study ends | December 2, 2035 |
| Registry record updated | April 22, 2026 |
| Trial ID | NCT07544563 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are adults with epilepsy who can attend in-person sessions at the Paris site, are not deaf, and can tolerate controlled sensory stimulation.
✕Probably not a fit
People who are deaf, those with other excluded neurological disorders, or those unable to travel to the Paris site are unlikely to benefit from taking part.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study measures behavioral and neurophysiological responses to controlled sensory stimulation delivered inside an acoustic chamber. Adults with epilepsy and healthy volunteers over 18 (excluding people with deafness or certain neurological conditions) will be exposed to stimuli like music while researchers record brain activity and behavioral responses. The protocol focuses on detailed phenotypic characterization rather than any therapeutic intervention, using in-person sessions to map individual response patterns. Collected data will be used to link specific stimulus features to changes in brain rhythms and symptom-related behaviors.
Why it matters
Potential benefit: If successful, the findings could help tailor noninvasive sensory approaches such as music-based interventions to improve mood or seizure-related brain activity in people with epilepsy.
How similar studies have gone: Previous research has shown that music and other sensory stimulation can alter brain rhythms and mood, but applying these methods specifically to characterize epilepsy phenotypes in an acoustic chamber is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * For patients : epilepsy * For healthy volunteers: age \> 18 yo Exclusion Criteria: * For patients and healthy volonteers : Deafness * For healthy volunteers : History of neurological conditions (including stroke, coma, epilepsy, neuro-inflammatory or neurodegenerative disease) or diagnosed cognitive impairment
Where it's running
-
GHU Paris Sainte Anne
Paris, France Recruiting
Study contacts
- Study coordinator: Viviane AWASSI
- Email: v.awassi@ghu-paris.fr
- Phone: +33145658486
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.