How common symptomatic gastroesophageal reflux is in Czech children aged 8–9 and 12–13

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This population-based, cross-sectional study recruits children aged 8–9 and 12–13 through selected schools in the Czech Republic and begins with a secure web-based questionnaire about reflux symptoms and related factors. Children reporting heartburn (pyrosis) or regurgitation enter a stepwise diagnostic pathway starting with a standardized 14-day proton pump inhibitor (PPI) trial including 14 days of baseline symptom recording and 14 days on PPI at age-appropriate doses. Those without a clear response undergo upper endoscopy to look for esophagitis or complications, and if endoscopy is normal or inconclusive they receive 24-hour pH-impedance monitoring to quantify reflux and symptom association. Final classifications (confirmed GERD, reflux hypersensitivity, or functional pyrosis) are combined with validated quality-of-life measures to produce population prevalence estimates and explore symptom burden and risk factors.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age group of 8 - 9 years and 12 - 13 years
* school attendance ability

Exclusion Criteria:

* psychomotor impairment

Where it's running

• Motol University Hospital
  Prague, Czechia Recruiting

Study contacts

• Study coordinator: Tereza Lerchova
• Email: terezadrskova@gmail.com
• Phone: +420775201573

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.