How common gummy smile and altered passive eruption are in young adults
Official title: Prevalence of Gummy Smile and Altered Passive Eruption in a Young Adult Population.
Run by University of Roma La Sapienza · NCT07548398 · Data updated 2026-11-12
This project will see how common gummy smile and altered passive eruption are in healthy adults aged 18–50 by measuring gum and tooth features and asking about cosmetic discomfort.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | University of Roma La Sapienza Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Roma, RM) |
| Status | Recruiting |
| Started | September 1, 2025 |
| Main results expected | October 1, 2026 |
| Study ends | December 1, 2026 |
| Registry record updated | April 29, 2026 |
| Trial ID | NCT07548398 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are periodontally healthy men and women aged 18–50 who have not had orthodontic treatment and have no prostheses or prior surgery in the second sextant.
✕Probably not a fit
Patients with active periodontitis, current orthodontic treatment, significant second-sextant crowding, relevant medications, pregnancy, oncologic treatment, or those unwilling to consent are unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational epidemiological study will examine patients presenting for their first clinical visit to determine the prevalence and local distribution of gummy smile and altered passive eruption, with special focus on the second sextant. Clinicians will record periodontal and aesthetic parameters, measure clinical crown dimensions and mucogingival junction position, and collect patient-reported aesthetic, psychological, and social discomfort. Data will be analyzed for correlations between gingival exposure, periodontal measures, and individual anatomical factors to identify patterns associated with altered passive eruption. No experimental treatments are given; the study relies on clinical assessment and interviews according to predefined inclusion and exclusion criteria.
Why it matters
Potential benefit: If successful, the study could help clinicians better recognize which anatomical features are linked to gummy smile and altered passive eruption, informing diagnosis and personalized treatment planning.
How similar studies have gone: Previous clinical and epidemiological reports have described altered passive eruption and gummy smile, so this work builds on established observations rather than testing an unproven treatment.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and female subjects; * Age between 18 and 50 years; * Periodontally healthy subjects; * Patients with no history of orthodontic treatment; * Patients without gingival hypertrophy or hyperplasia. Exclusion Criteria: * Age \< 18 or \> 50 years; * Patients diagnosed with Stage I-IV periodontitis; * Patients currently undergoing orthodontic treatment; * Patients with severe dental crowding in the second sextant; * Patients taking medications associated with gingival hypertrophy or -hyperplasia; * Patients unwilling to provide informed consent; * Patients with fixed or removable prostheses in the second sextant; * Patients with a history of surgical procedures in the second sextant; * Patients with uncontrolled diabetes or neuropsychiatric disorders; * Patients with infectious diseases; * Pregnant or breastfeeding women, or those with suspected pregnancy; * Patients taking bisphosphonates; * Oncologic patients and those undergoing head and neck radiotherapy or receiving chemotherapy; * Patients with alcohol or drug abuse.
Where it's running
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Sapienza università di Roma
Roma, Rm, Italy Recruiting
Study contacts
- Study coordinator: Fabrizio Guerra
- Email: fabrizio.guerra@uniroma1.it
- Phone: 3283150627
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Gummy smile correction with esthetic crown-lengthening surgery
This study tests whether esthetic crown-lengthening surgery can stabilize gum tissue in adults with altered passive eruption and excessive gingival display.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.