How common gummy smile and altered passive eruption are in young adults
Prevalence of Gummy Smile and Altered Passive Eruption in a Young Adult Population.
This project will see how common gummy smile and altered passive eruption are in healthy adults aged 18–50 by measuring gum and tooth features and asking about cosmetic discomfort.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | University of Roma La Sapienza Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Roma, RM) |
| Trial ID | NCT07548398 on ClinicalTrials.gov |
What this trial studies
This observational epidemiological study will examine patients presenting for their first clinical visit to determine the prevalence and local distribution of gummy smile and altered passive eruption, with special focus on the second sextant. Clinicians will record periodontal and aesthetic parameters, measure clinical crown dimensions and mucogingival junction position, and collect patient-reported aesthetic, psychological, and social discomfort. Data will be analyzed for correlations between gingival exposure, periodontal measures, and individual anatomical factors to identify patterns associated with altered passive eruption. No experimental treatments are given; the study relies on clinical assessment and interviews according to predefined inclusion and exclusion criteria.
Who should consider this trial
Good fit: Ideal candidates are periodontally healthy men and women aged 18–50 who have not had orthodontic treatment and have no prostheses or prior surgery in the second sextant.
Not a fit: Patients with active periodontitis, current orthodontic treatment, significant second-sextant crowding, relevant medications, pregnancy, oncologic treatment, or those unwilling to consent are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, the study could help clinicians better recognize which anatomical features are linked to gummy smile and altered passive eruption, informing diagnosis and personalized treatment planning.
How similar studies have performed: Previous clinical and epidemiological reports have described altered passive eruption and gummy smile, so this work builds on established observations rather than testing an unproven treatment.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and female subjects; * Age between 18 and 50 years; * Periodontally healthy subjects; * Patients with no history of orthodontic treatment; * Patients without gingival hypertrophy or hyperplasia. Exclusion Criteria: * Age \< 18 or \> 50 years; * Patients diagnosed with Stage I-IV periodontitis; * Patients currently undergoing orthodontic treatment; * Patients with severe dental crowding in the second sextant; * Patients taking medications associated with gingival hypertrophy or -hyperplasia; * Patients unwilling to provide informed consent; * Patients with fixed or removable prostheses in the second sextant; * Patients with a history of surgical procedures in the second sextant; * Patients with uncontrolled diabetes or neuropsychiatric disorders; * Patients with infectious diseases; * Pregnant or breastfeeding women, or those with suspected pregnancy; * Patients taking bisphosphonates; * Oncologic patients and those undergoing head and neck radiotherapy or receiving chemotherapy; * Patients with alcohol or drug abuse.
Where this trial is running
Roma, RM
- Sapienza università di Roma — Roma, Rm, Italy (Recruiting)
Study contacts
- Study coordinator: Fabrizio Guerra
- Email: fabrizio.guerra@uniroma1.it
- Phone: 3283150627
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.