How belief changes the pain we feel when we see others hurt

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Healthy adult volunteers are randomly assigned to one of three groups: no-treatment control, a placebo nasal spray described as oxytocin, or a real oxytocin nasal spray. While undergoing functional MRI, participants watch naturalistic videos of people in painful situations and rate the pain they perceive. Behavioral responses will be transformed into analgesia-weighted scores, and neural data will include voxel-wise activity, multivariate predictive patterns, and directed functional connectivity analyses. Group comparisons will test how cognitive belief and oxytocin change subjective empathic pain and the brain network interactions that support it.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* (1) Healthy subjects without any past or present psychiatric or neurological disorders; (2) Healthy subjects without any current psychotherapeutic medication.

Exclusion Criteria:

* (1) Participant with any past or present psychiatric or neurological disorders; (2)Participant with any current psychotherapeutic medication.

Where it's running

• Weihua Zhao
  Chengdu, Sichuan, China Recruiting
• University of Electronic Science and Technology of China
  Chengdu, China Enrolling by invitation

Study contacts

• Study coordinator: Weihua Zhao
• Email: zarazhao@uestc.edu.cn
• Phone: +8618780247797

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.