How antibiotic-resistant bacteria move between people, pets, and the environment
Official title: Dynamics of AMR Spread, Persistence and Evolution Between Humans, Animals and Their Environment
Run by Assistance Publique - Hôpitaux de Paris · NCT06262009 · Data updated 2026-11-12
This project will test whether people who live with dogs pick up antibiotic-resistant bacteria from their pets.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 525 (estimated) |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Maisons-Alfort) |
| Status | Recruiting |
| Started | December 15, 2025 |
| Main results expected | September 2028 |
| Study ends | March 2029 |
| Registry record updated | April 23, 2026 |
| Trial ID | NCT06262009 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are French-speaking adults or children who own a dog recorded for surgery at the National Veterinary School Alfort and plan to live with that dog in the same household for the next three months and can give informed consent.
✕Probably not a fit
People who do not live with a dog, cannot provide consent, are under legal guardianship or custody restrictions, lack social security affiliation, or do not speak French are unlikely to be eligible or to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
DYASPEO is an observational project in France that follows households where a dog and its owners live together to track transmission of extended-spectrum cephalosporin- and carbapenem-resistant bacteria. The team will collect stool samples from humans and dogs and combine microbiology, whole-genome sequencing, microbiome analysis, epidemiology, modelling, and social science interviews to map transmission routes. Sampling and analysis focus on carriage and genetic relatedness of resistant Enterobacteriaceae over time. The goal is to clarify how often and by which pathways companion animals contribute to human antimicrobial resistance carriage.
Why it matters
Potential benefit: If successful, the project could help prevent human acquisition of resistant bacteria from pets by identifying transmission pathways and informing practical hygiene and veterinary measures.
How similar studies have gone: Previous studies have found higher carriage of resistant Enterobacteriaceae in farmers exposed to food animals, but direct transmission between companion animals and their owners has been much less studied and remains uncertain.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult or child planning to live in the same household as his/her dog during the three months following inclusion. * Planning to live in the same habitat in the next three months following inclusion (except for holidays). * Written consent of all adults and of at least one of the two parents for minors under parental authority. A different information note will be elaborated for each age category (6-10 yr-old, 10-15 yr-old and 16-18 yr-old). * Owning a dog recorded for a surgery at the National Veterinary School Exclusion Criteria: * Lack of signed informed consent * Subject in alternating custody * Subject under legal protection (guardianship) * Subject deprived of liberty under judicial constraint * Subject undergoing psychiatric care * Lack of affiliation to a social security scheme * Volunteers who do not speak/write French
Where it's running
-
the National Veterinary School Alfort
Maisons-Alfort, France Recruiting
Study contacts
- Principal investigator: Jean-Yves Madec, PHD — Anses
- Study coordinator: Jean-Yves Madec, PHD
- Email: Jean-Yves.MADEC@anses.fr
- Phone: 06 85 08 93 30
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.