How a quick sugar dose affects choroidal thickness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, repeated-measures study in which fasting participants will undergo a baseline macular OCT scan of the right eye using the Heidelberg Spectralis. Participants will then consume 30 grams of glucose as glucose tablets and remain onsite for three hours. Macular OCT scans will be repeated every 30 minutes after sugar intake to track choroidal thickness over time. Subjects must abstain from food during the visit and avoid caffeine for 12 hours prior; people with diabetes, pre-diabetes, retinal pathology, significant refractive error, or other systemic/ocular conditions are excluded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* In order to be eligible for enrolment, each subject must have less than 6 diopters of spherical equivalent refractive error, and have no existing diagnosis of diabetes or pre-diabetes.

Exclusion Criteria:

* Any potential subject with known retinal pathology will be excluded. Any potential subject with any other known systemic or ocular conditions that may impact their ability to participate in the study or provide generalizable data will also be excluded.

Where it's running

• Southern College of Optometry
  Memphis, Tennessee, United States Recruiting

Study contacts

• Study coordinator: Morgan Ollinger, OD, MS
• Email: mollinger@sco.edu
• Phone: 9017223377

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.