Clinical trial Recruiting at 10 sites Observational Ages 18 to 40 Women only

How a prior early abortion affects later pregnancy complications and outcomes

Official title: Effects of Prior Induced Termination of Pregnancy on Complications and Pregnancy Outcomes.

Run by National Research Institute for Family Planning, China · NCT04183829 · Data updated 2026-11-12

This project will try to see if having an early induced abortion (before 12 weeks) changes the risk of complications or outcomes in later pregnancies for women who can be followed over time.

Quick facts

Study typeObservational
Ages18 Years to 40 Years
SexWomen only
Enrollment20000 (estimated)
SponsorNational Research Institute for Family Planning, China
Government
Locations12 sites (Zhongshan, Guangdong and 11 other locations)
StatusRecruiting
StartedJune 1, 2019
Main results expectedDecember 2027
Study endsJune 2028
Registry record updatedSeptember 12, 2025
Trial IDNCT04183829 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Women under 40 who had an induced abortion before 12 weeks, are permanent residents at a participating site, can communicate and consent, and are willing to complete follow-up are ideal candidates.

Probably not a fit

Women over 40, those with a history of adverse pregnancy or childbirth, or those who cannot complete follow-up are not eligible and would not benefit from participation or the study findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective multicenter cohort enrolling women who had an induced abortion in early pregnancy (<12 weeks) at three hospitals across China and following them forward to document subsequent pregnancy outcomes. Investigators will collect clinical information and record pregnancy complications through scheduled follow-ups and medical records. Eligible participants are permanent local residents under 40 without a prior history of adverse pregnancy or childbirth and who can provide informed consent and reliable contact information. The multicenter design is intended to capture regional variation in real-world outcomes rather than test a specific treatment intervention.

Why it matters

Potential benefit: If successful, the results could help clinicians and patients better understand and discuss risks after an early abortion and guide pregnancy care to reduce complications.

How similar studies have gone: Some retrospective studies have reported small associations between prior abortion and later outcomes, but prospective multicenter evidence is limited and results are mixed.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* women have induced abortion in early pregnancy (\<12 weeks of gestation).
* permanent population and no tendency to move.
* normal language expression and understanding ability, able to understand research content.
* be able and willing to provide written informed consent and effective contact information, and be willing to cooperate with follow-up investigations.

Exclusion Criteria:

* above the age of 40
* with history of adverse pregnancy and childbirth

Where it's running

  • Zhongshan Boai Hospital
    Zhongshan, Guangdong, China
    Recruiting
  • Zhangjiakou Maternal and Child Health Hospital
    Zhangjiakou, Hebei, China
    Recruiting
  • Daqing People's Hospital
    Daqing, Heilongjiang, China
    Recruiting
  • Changzhou Maternal and Child Health Hospital
    Changzhou, Jiangsu, China
    Recruiting
  • Yangzhou Maternal and Child Health Hospital
    Yangzhou, Jiangsu, China
    Recruiting
  • People's Hospital of Inner Mongolia Autonomous Region
    Hohhot, Mongolia Autonomous, China
    Recruiting
Show 6 more locations
  • Zaozhuang Maternal and Child Health Hospital
    Zaozhuang, Shandong, China
    Recruiting
  • Taiyuan Maternal and Child Health Hospital
    Taiyuan, Shanxi, China
    Recruiting
  • Chongqing Health Center for Women and Children
    Chongqing, China
    Recruiting
  • Shenzhen Luohu Maternity and Child Healthcare Hospital
    Shenzhen, China
    Recruiting
  • Qingdao Maternal and Child Health Hospital
    Qingdao, Shandong, China
    Completed
  • Tanggu Maternal and Child Health Hospital
    Tanggu, Tianjin Municipality, China
    Completed

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.