Hormone treatment for postmenopausal women and its effects on Alzheimer's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates the effects of hormone replacement therapy on dementia in postmenopausal women. It aims to analyze the degradation products of amyloid in the cerebrospinal fluid and blood to understand the relationship between menopause and the onset of Alzheimer's disease. Participants will include postmenopausal women aged 40 to 65, both with and without a history of breast cancer. The study will involve blood sample collection to assess metabolic changes associated with hormonal therapy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* postmenopausal women
* 40 - 65 years

Exclusion Criteria:

* Longer than 10 years in menopause
* thyroid dysfunction
* hypertension
* medical history of psychiatric comorbidity
* Alcohol and/or drug abuse
* medical history of neurologic symptoms with cognitive symptoms

Where it's running

• Ghent university hospital
  Ghent, Belgium Recruiting

Study contacts

• Principal investigator: Herman Depypere, MD — University Hospital, Ghent
• Study coordinator: Eline Meireson, Msc
• Email: eline.meireson@uzgent.be
• Phone: 0032 9 332 78 17

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.