Hong Kong register and 3-year integrated care program for Chinese adults with diabesity
Official title: Establishment of Hong Kong Diabesity Register and a 3-year Randomized Clinical Trial for the Investigation of the Effectiveness of a Multicomponent Integrated Care Program in Chinese With Diabesity
Run by Chinese University of Hong Kong · NCT07039279 · Data updated 2026-11-12
This program will test whether a 3-year team-based approach (medical therapy, dietitian and psychologist support, e-care with an AI chatbot, biofeedback and peer support) helps Chinese adults aged 18–50 with type 2 diabetes and obesity lose weight and improve physical and mental health.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong) |
| Status | Recruiting |
| Started | October 22, 2025 |
| Main results expected | October 31, 2030 |
| Study ends | December 31, 2030 |
| Registry record updated | March 3, 2026 |
| Trial ID | NCT07039279 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Hong Kong Chinese adults aged 18–50 with type 2 diabetes and obesity (BMI ≥27.5 kg/m2 and/or waist circumference ≥80 cm for women or ≥90 cm for men) who can read Chinese and use smartphone/web-based programs.
✕Probably not a fit
Patients with type 1 diabetes, active or recent malignancy, life expectancy under 12 months, those unable to use smartphone/web tools or who cannot read Chinese, and anyone judged by investigators as medically ineligible are unlikely to benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The project first creates a Hong Kong register of Chinese adults with diabesity and then recruits participants from that register into a 3-year randomized clinical trial. Enrolled participants at the Prince of Wales Hospital will be randomized to a multicomponent integrated care program delivered by an endocrinologist, dietitian, psychologist and research assistant, using medical therapy, cognitive behavioural therapy, e-care tools (TourHeart+), an AI chatbot, biofeedback and peer support, versus usual care. The primary outcome is weight reduction over three years, and secondary outcomes include cardiometabolic risk factors, diabetes distress, lifestyle behaviours and sleep hygiene. The design is pragmatic and leverages digital platforms to deliver interventions and collect clinical and patient-reported data in a real-world setting.
Why it matters
Potential benefit: If successful, the program could help people with diabesity lose meaningful weight, improve metabolic health and reduce diabetes-related emotional distress, potentially lowering long-term complications.
How similar studies have gone: Multidisciplinary programs combining medical, nutritional and psychological care have shown benefits for weight and glycemic control, but long-term randomized trials that combine e-care, AI chatbots and biofeedback in diabesity are relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Type 2 diabetes; 2. Obesity reaching action level as defined as body mass index (BMI) ³27.5 kg/m2 and/or waist circumference (WC) ³80cm in women and ³90cm in men; 3. Age between 18 and 50 years; 4. Able to conversate with smartphone technology and web-based program. 5. Able to read Chinese and communicate using Chinese. Exclusion Criteria: 1. Type 1 diabetes; 2. Active malignant disease including those with history of malignant disease less than 5 years of disease-free duration; 3. Life expectancy less than 12 months; 4. Any medical illness or condition as judged by the investigators as ineligible to participate the study.
Where it's running
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Department of Medicine and Therapeutics, The Chinese University of Hong Kong (CUHK), Ward 3M, Diabetes and Endocrine Research Centre, 3/F Day Treatment Block and Children Wards (Old Block), Prince of Wales Hospital
Hong Kong, Hong Kong Recruiting
Study contacts
- Study coordinator: Alice Pik Shan Kong, MD
- Email: alicekong@cuhk.edu.hk
- Phone: +852 3505 2648
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Hong Kong Diabesity Register
This project will collect health data to see how type 2 diabetes with obesity changes over time in adults aged 18–50 who can read Chinese and use a smartphone.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.