Homecare intervention to improve outcomes for stroke patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The SHIFT trial aims to evaluate the effectiveness of a homecare intervention for stroke patients aged 18-75 who have three or more social determinants of health (SDOH) risk factors. This randomized, blinded trial will compare the outcomes of patients receiving the SHIFT intervention, which includes support from community health workers, social workers, and nurses, against those receiving usual care. The primary focus is on improving functional outcomes, physiological measures, and exploring epigenetic biomarkers over a period of six months to one year post-stroke.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Ischemic stroke (arterial subtypes) or primary intracerebral hemorrhage (excluding diagnosis of probable cerebral amyloid angiopathy by Boston Criteria)
* African American/Black or Hispanic race-ethnicity
* Age 18-75 years old
* Have at least 3 SDOH barriers from within the 5 SDOH domains (Social and Community, Education, Economic, neighborhood/environment, Health Care)
* Have a discharge plan to 1) home with or without home services, or 2) acute rehabilitation with plan to return home after
* Pre-stroke Modified Rankin Scale score of ≤3
* Residence in New York City.
* English or Spanish speaking.
* Can provide informed consent and engage in the initial assessment prior to stroke discharge
* Lives in a household with a telephone, and has a caregiver (family member or Home Health Aide) if not fully independent on discharge. If the patient requires a family member to assist with activities of daily living or decision-making, the family member must state a willingness to be present at home visits where their assistance is needed.

Exclusion Criteria:

* Discharge disposition to a long-term care facility.
* Diagnosis of dementia or other neurological diagnosis that affects cognition
* Diagnosis of active major depression
* Aphasia severe enough to preclude initial examination
* Impaired level of consciousness at initial cognitive assessment
* Subarachnoid hemorrhage
* Diagnosis of probable cerebral amyloid angiopathy by Boston criteria
* Life expectancy less than 1 year

Where it's running

• Columbia University Medical Center
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Olajide Williams, MD — Columbia University
• Study coordinator: Olajide Williams, MD
• Email: ow11@cumc.columbia.edu
• Phone: (212) 305-1710

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals

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• Web-based therapy using action observation and mirror therapy for arm weakness after stroke

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• Remote Ischaemic Conditioning for Fatigue After Stroke 2

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• Dual-task balance training plus computer-based cognitive training after stroke

  In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.

  Recruiting Matia Foundation · San Sebastián, GUIPUZCOA · NCT07913620

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.