Home exercise program to improve recovery after vaginal prolapse repair
PREPARE: Perioperative REhabilitation Around Vaginal Prolapse RepAir Surgery for Recovery Enhancement
This research will test whether a 6-week home pelvic floor exercise program helps people having transvaginal prolapse repair get back to normal daily activities after surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 92 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | University of New Mexico Academic / other |
| Locations | 1 site (Albuquerque, New Mexico) |
| Trial ID | NCT07265973 on ClinicalTrials.gov |
What this trial studies
This randomized study assigns people undergoing transvaginal prolapse repairs (sacrospinous ligament suspension, uterosacral ligament suspension, or Manchester procedure) to either standard perioperative care or standard care plus a standardized 6-week home pelvic floor exercise program. Participants are randomized 1:1 and will follow easy-to-do exercises at home with video access. The trial focuses on postoperative physical functioning in everyday tasks like walking and stair use rather than isolated strength measures. The program intentionally omits daily maximal pelvic floor contractions and aims to offer a reproducible, standardized perioperative exercise approach.
Who should consider this trial
Good fit: Adults (≥18 years) who speak English or Spanish, have stage 2–4 uterovaginal or vault prolapse, and are scheduled for one of the specified transvaginal repairs at the University of New Mexico Hospital.
Not a fit: Patients already in pelvic floor physical therapy, those unable to perform the exercises or use video/Internet, those with dementia or unable to complete questionnaires, or those having certain concurrent pelvic procedures are unlikely to benefit from or be eligible for this program.
Why it matters
Potential benefit: If successful, the program could offer a simple, home-based way to improve postoperative physical functioning and reduce deconditioning after vaginal prolapse repair.
How similar studies have performed: Previous pelvic floor physical therapy studies have been heterogeneous with mixed results, so this specific standardized perioperative home-exercise approach is relatively novel and not yet proven.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects are ≥ 18 years of age * English or Spanish speaking * Stage 2, 3 or 4 uterovaginal or vaginal vault prolapse. * Patient scheduled to undergo transvaginal sacrospinous ligament suspension, uterosacral ligament suspension, or Manchester procedure at The University of New Mexico Hospital. Exclusion Criteria: * Inability to speak English or Spanish * Currently enrolled in Pelvic floor physical therapy * Inability to perform the home exercises * Dementia * Inability to fill out questionnaires * Inability to access video via internet * Undergoing concomitant surgeries that involve: InterStim, bladder hydrodistension/fulguration, pelvic floor Botox, mesh excision/complications.
Where this trial is running
Albuquerque, New Mexico
- University of New Mexico Hospital — Albuquerque, New Mexico, United States (Recruiting)
Study contacts
- Principal investigator: Sarah Jeney, MD
- Study coordinator: Rachel E Moore, MD
- Email: racemoore@salud.unm.edu
- Phone: 720-394-9986
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.