Home exercise program to improve recovery after vaginal prolapse repair
Official title: PREPARE: Perioperative REhabilitation Around Vaginal Prolapse RepAir Surgery for Recovery Enhancement
Run by University of New Mexico · NCT07265973 · Data updated 2026-11-12
This research will test whether a 6-week home pelvic floor exercise program helps people having transvaginal prolapse repair get back to normal daily activities after surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 56 (estimated) |
| Sponsor | University of New Mexico Academic / other |
| Locations | 1 site (Albuquerque, New Mexico) |
| Status | Recruiting |
| Started | November 24, 2025 |
| Main results expected | June 25, 2027 |
| Study ends | June 25, 2028 |
| Registry record updated | August 6, 2026 |
| Trial ID | NCT07265973 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18 years) who speak English or Spanish, have stage 2–4 uterovaginal or vault prolapse, and are scheduled for one of the specified transvaginal repairs at the University of New Mexico Hospital.
✕Probably not a fit
Patients already in pelvic floor physical therapy, those unable to perform the exercises or use video/Internet, those with dementia or unable to complete questionnaires, or those having certain concurrent pelvic procedures are unlikely to benefit from or be eligible for this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized study assigns people undergoing transvaginal prolapse repairs (sacrospinous ligament suspension, uterosacral ligament suspension, or Manchester procedure) to either standard perioperative care or standard care plus a standardized 6-week home pelvic floor exercise program. Participants are randomized 1:1 and will follow easy-to-do exercises at home with video access. The trial focuses on postoperative physical functioning in everyday tasks like walking and stair use rather than isolated strength measures. The program intentionally omits daily maximal pelvic floor contractions and aims to offer a reproducible, standardized perioperative exercise approach.
Why it matters
Potential benefit: If successful, the program could offer a simple, home-based way to improve postoperative physical functioning and reduce deconditioning after vaginal prolapse repair.
How similar studies have gone: Previous pelvic floor physical therapy studies have been heterogeneous with mixed results, so this specific standardized perioperative home-exercise approach is relatively novel and not yet proven.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects are ≥ 18 years of age * English or Spanish speaking * Stage 2, 3 or 4 uterovaginal or vaginal vault prolapse. * Patient scheduled to undergo transvaginal sacrospinous ligament suspension, uterosacral ligament suspension, or Manchester procedure at The University of New Mexico Hospital. Exclusion Criteria: * Inability to speak English or Spanish * Currently enrolled in Pelvic floor physical therapy * Inability to perform the home exercises * Dementia * Inability to fill out questionnaires * Inability to access video via internet * Undergoing concomitant surgeries that involve: InterStim, bladder hydrodistension/fulguration, pelvic floor Botox, mesh excision/complications.
Where it's running
-
University of New Mexico Hospital
Albuquerque, New Mexico, United States Recruiting
Study contacts
- Principal investigator: Kate Meriwether, MD
- Study coordinator: Rachel E Moore, MD
- Email: racemoore@salud.unm.edu
- Phone: 720-394-9986
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.