Home care for patients receiving stem cell transplants
Pilot Trial of Homebound Stem Cell Transplantation
This study is testing whether home care with remote check-ins can help patients recovering from stem cell transplants feel better and stay safe.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 91 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Memorial Sloan Kettering Cancer Center Academic / other |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT02671448 on ClinicalTrials.gov |
What this trial studies
This study investigates the feasibility and effects of providing care for patients with plasma cell dyscrasia in a home setting after undergoing autologous stem cell transplantation (ASCT). The approach includes home monitoring through teleconsult visits and the use of patient and caregiver reported outcomes to assess recovery. Previous studies have indicated that home care can enhance patient satisfaction and reduce infection risks, and this trial aims to evaluate these benefits specifically at Memorial Sloan Kettering Cancer Center.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-80 diagnosed with plasma cell dyscrasia who are undergoing autologous HSCT and have adequate caregiver support.
Not a fit: Patients who do not have a suitable home environment or adequate caregiver support may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve recovery outcomes and patient satisfaction for those undergoing stem cell transplants.
How similar studies have performed: Other studies have shown success with home care approaches for post-transplant patients, suggesting this method is promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of Plasma cell dyscrasia * Treatment plan including Autologous HSCT * 18-80 years of age * Appropriate homebound setting as defined by one of the following: * Lodging at the MSK Residence. * Staying at home or a "home equivalent" in any one of the zip codes as outlined in the appendix. Home equivalent is defined as a residence which may or may not be the primary residence of the patient. * "Home equivalent" must pass the "Home Environment Screening Tool" for homebound stem cell transplantation (not required for other MSK recognized lodging facility). * Adequate caregiver support as defined by: * Single or multiple informal caregivers willing and able to provide 24 hour a day, seven day a week supervision of the transplant recipient in their home or "home-like" environment. * Caregiver willing and able to fulfill the basic stem cell transplant caregiver education requirements as determined by caregiver and healthcare team, including social worker * Have Wi-Fi connection * Appropriate third party payer coverage for "Homebound Stem Cell Transplant Program" * Both patient and caregiver willing to give and sign informed consent. Exclusion Criteria: * Patients with a documented active infection prior to starting their preparative regimen. This includes grade 3 or higher viral, bacterial, or fungal infection. * Uncontrolled arrhythmias * Active or uncontrolled pulmonary disease * Karnofsky Performance Scale (KPS) score \<80 * Sorror Co-morbidity index ≥ 4 except in patients with history of resected cancers * Creatinine clearance (calculated or measured) of \< 50 cc/minute * Inability of patient or caregiver to speak or read English (we currently do not have the manpower to translate nor staff a multilingual homebound stem cell transplant program with adequate educational materials). * Inadequate housing arrangements * Inadequate caregiver arrangements
Where this trial is running
New York, New York
- Memorial Sloan Kettering Cancer Center — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: Heather Landau, MD — Memorial Sloan Kettering Cancer Center
- Study coordinator: Heather Landau, MD
- Email: ABMTTrials@mskcc.org
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.