Home breast mapping with the Feminai adhesive patch to detect suspicious lesions

Evaluation of the Safety and Efficacy of a Wearable Device Based on Thermometry and Impedance Technology for Breast Mapping and Detecting Suspicious Breast Lesions Using Feminai 1.0

Observational Feminai · NCT07220863

This project will test whether an at-home Feminai adhesive patch that measures skin temperature and electrical impedance can help detect suspicious breast lesions in women ages 25–75 undergoing screening mammography or biopsy.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages25 Years to 75 Years
SexFemale
SponsorFeminai Industry-sponsored
Locations1 site (Frisco, Texas)
Trial IDNCT07220863 on ClinicalTrials.gov

What this trial studies

This prospective observational study will enroll up to 300 women aged 25–75, split between routine screening (BI-RADS 1–2) and those scheduled for biopsy after concerning mammograms (BI-RADS 4–5). Trained staff will apply the Feminai adhesive patch in a private room during a single study visit to record skin-surface temperature and electrical impedance and generate a breast map. Feminai results will be compared with contemporaneous mammography and, when available, biopsy results to estimate sensitivity and negative predictive value. The device is investigational and intended to support, not replace, standard diagnostic tests.

Who should consider this trial

Good fit: Women aged 25–75 who are presenting for routine screening mammography (BI-RADS 1–2) or who are scheduled for biopsy after a higher-concern mammogram (BI-RADS 4–5), and who are able to provide consent and comply with study procedures, are the intended participants.

Not a fit: Women currently undergoing treatment for breast cancer, who are pregnant or breastfeeding, who have breast implants or recent breast surgery, metal implants, or very large cup sizes are unlikely to be eligible or to receive benefit from this device.

Why it matters

Potential benefit: If successful, Feminai could offer a noninvasive at-home mapping tool that helps flag suspicious breast lesions earlier or reduce unnecessary follow-up procedures.

How similar studies have performed: Previous small studies of thermal and electrical-impedance wearable approaches have produced mixed results, so this approach is promising but not yet proven.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

General:

1. Females aged 25-75 years.
2. Able to comply with study procedures and follow-up requirements.
3. Willing and able to provide informed consent.

Additional for Group 1 (up to N=150):

1. Presenting for routine mammography/tomosynthesis breast cancer screening according to national/regional guidelines.
2. Most recent mammography result - BIRADS 1 or 2

Additional for Group 2 (up to N=150):

1\. Presenting for biopsy following BIRADS 4-5 mammogram

Exclusion Criteria:

1. History of current treatment for breast cancer.
2. Pregnancy or lactation.
3. Presence of any implanted metal.
4. Any condition that, in the opinion of the investigator, may interfere with the participant's ability to comply with study requirements or may pose a risk to the participant.
5. Has breast enhancements (e.g. implants or injections)
6. Subjects who have undergone surgery (e.g. lumpectomy or mastectomy) in the last year at the time of study enrollment
7. No subject will be allowed to enroll in this trial more than once.
8. Cup size larger than E in US-based sizing charts.

Where this trial is running

Frisco, Texas

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast Cancer AwarenessBreast lesionsBreast mappingHome breast examinationWearable patchThermometryBioimpedance
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.