Clinical trial Recruiting at 1 site Interventional Ages 6 to 17

Home-based pulmonary rehabilitation for children after tuberculosis

Official title: Paediatric Post-TB Home-based Pulmonary Rehabilitation Feasibility Study

Run by University of Iowa · NCT07097961 · Data updated 2026-11-12

This study will test a 6-week home pulmonary rehabilitation program to see if children aged 6–17 who finished treatment for pulmonary TB can follow the program and improve walking distance and quality of life.

Quick facts

Study typeInterventional
Ages6 Years to 17 Years
SexAll
Enrollment40 (estimated)
SponsorUniversity of Iowa
Academic / other
Locations1 site (Kampala)
StatusRecruiting
StartedJuly 29, 2025
Main results expectedFebruary 23, 2026
Study endsFebruary 23, 2026
Registry record updatedAugust 11, 2025
Trial IDNCT07097961 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Children aged 6–17 with previously diagnosed post-TB lung disease who can do mild-to-moderate physical activity and will stay in the Kampala study catchment area are ideal candidates.

Probably not a fit

Children with active respiratory infection, those already in another rehabilitation program, or those living outside the Kampala metropolitan area are unlikely to be eligible or to benefit from this home-based program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-arm feasibility study in Kampala, Uganda delivers a 6-week home-based pulmonary rehabilitation program to children aged 6–17 with post-TB lung disease. Participants receive exercise instructions, a pedometer, and are asked to perform twice-weekly walking and wall-sit exercises with weekly follow-up by phone or home visit. Baseline and 6-week assessments include a 6-minute walk test and the St. George's Respiratory Questionnaire to measure exercise capacity and respiratory quality of life. Participants are recruited from an existing cohort or by clinician referral and must remain in the study catchment area for the study period.

Why it matters

Potential benefit: If successful, the program could provide an accessible way to improve exercise capacity and quality of life for children with post-TB lung disease in low-resource settings.

How similar studies have gone: Pulmonary rehabilitation has shown benefit in adults with chronic lung disease and post-TB lung disease, but similar home-based programs have not been well tested in children, especially in low-resource settings.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged 6-17 years
* Previously diagnosed with post-TB lung disease,
* Willing to remain in the study catchment area during the study period
* Able to participate in mild-to-moderate physical activity (late inclusion criterion)

Exclusion Criteria:

* Currently participating in another rehabilitation program
* Residence outside the Kampala metropolitan area
* Active respiratory infection (late exclusion criterion)

Where it's running

  • MU-JHU Care Ltd/MU-JHU Research Collaboration
    Kampala, Uganda
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.