Home-based pulmonary rehabilitation for children after tuberculosis
Official title: Paediatric Post-TB Home-based Pulmonary Rehabilitation Feasibility Study
Run by University of Iowa · NCT07097961 · Data updated 2026-11-12
This study will test a 6-week home pulmonary rehabilitation program to see if children aged 6–17 who finished treatment for pulmonary TB can follow the program and improve walking distance and quality of life.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 6 Years to 17 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | University of Iowa Academic / other |
| Locations | 1 site (Kampala) |
| Status | Recruiting |
| Started | July 29, 2025 |
| Main results expected | February 23, 2026 |
| Study ends | February 23, 2026 |
| Registry record updated | August 11, 2025 |
| Trial ID | NCT07097961 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 6–17 with previously diagnosed post-TB lung disease who can do mild-to-moderate physical activity and will stay in the Kampala study catchment area are ideal candidates.
✕Probably not a fit
Children with active respiratory infection, those already in another rehabilitation program, or those living outside the Kampala metropolitan area are unlikely to be eligible or to benefit from this home-based program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-arm feasibility study in Kampala, Uganda delivers a 6-week home-based pulmonary rehabilitation program to children aged 6–17 with post-TB lung disease. Participants receive exercise instructions, a pedometer, and are asked to perform twice-weekly walking and wall-sit exercises with weekly follow-up by phone or home visit. Baseline and 6-week assessments include a 6-minute walk test and the St. George's Respiratory Questionnaire to measure exercise capacity and respiratory quality of life. Participants are recruited from an existing cohort or by clinician referral and must remain in the study catchment area for the study period.
Why it matters
Potential benefit: If successful, the program could provide an accessible way to improve exercise capacity and quality of life for children with post-TB lung disease in low-resource settings.
How similar studies have gone: Pulmonary rehabilitation has shown benefit in adults with chronic lung disease and post-TB lung disease, but similar home-based programs have not been well tested in children, especially in low-resource settings.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 6-17 years * Previously diagnosed with post-TB lung disease, * Willing to remain in the study catchment area during the study period * Able to participate in mild-to-moderate physical activity (late inclusion criterion) Exclusion Criteria: * Currently participating in another rehabilitation program * Residence outside the Kampala metropolitan area * Active respiratory infection (late exclusion criterion)
Where it's running
-
MU-JHU Care Ltd/MU-JHU Research Collaboration
Kampala, Uganda Recruiting
Study contacts
- Principal investigator: Greta L Becker, MD — University of Iowa
- Study coordinator: Greta L Becker, MD
- Email: greta-becker@uiowa.edu
- Phone: 15635529422
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.