Home-based high-speed bodyweight training for people with Parkinson's disease
Effects of Remotely Supervised Home-based High-speed Bodyweight Resistance Training on Bradykinesia in Individuals With Parkinson's Disease: A Randomized Clinical Trial
This study is testing if a fast-paced home workout program can help people with Parkinson's disease move better and feel more active.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 46 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | Federal University of Minas Gerais Academic / other |
| Locations | 1 site (Belo Horizonte, Minas Gerais) |
| Trial ID | NCT06646523 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of home-based high-speed bodyweight resistance training on individuals with Parkinson's disease, focusing on reducing bradykinesia and improving mobility. Participants will engage in remotely supervised training sessions designed to enhance movement speed and overall physical function. The study will utilize a randomized controlled trial design, with outcomes measured using standardized assessments of motor function and quality of life. Statistical analyses will be conducted to evaluate the effectiveness of the intervention compared to a control group performing exercises at a usual speed.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 50 and older with a diagnosis of Parkinson's disease, classified between stages 1-3 of the Hoehn & Yahr Scale, and experiencing bradykinesia.
Not a fit: Patients who are highly active or have advanced stages of Parkinson's disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve mobility and quality of life for patients with Parkinson's disease.
How similar studies have performed: While similar high-speed training approaches have shown benefits in elderly populations, this specific application in Parkinson's disease is novel and untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria * ≥50 years old; * Parkinson's disease diagnosed by a neurologista; * classified between stages 1-3 of the modified Hoehn \& Yahr Scale; * present bradykinesia identified by items 3.8 (Leg Agility) and/or 3.14 (Global Spontaneity of Movement - Body Bradykinesia) of the motor examination of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) with a minimum score of 1 out of 4 points in at least one of the items; * taking antiparkinsonian medication, and who have been medically stable * are classified as inactive or insufficiently active; have ability to walk independently without assistive devices; and have written medical permission to allow them to participate in the study. The Centers for Disease Control and Prevention classification will be used to determine if an individual is inactive or insufficiently active. Participants will be asked about the exercises they performed most often over the last 4 weeks, including their frequency and duration. Individuals who report that they have performed physical exercise over the last month at least five times per week for more than 30 min at a moderate intensity or at least three times per week for at least 20 min at a vigorous intensity will be classified as having moderate or vigorous exercise levels, respectively. Individuals who report not having practiced any exercise over the last month will be classified as inactive. Those who report doing physical exercise over the last month that is not classified as vigorous or moderate intensity will be classified as insufficiently active. Exclusion Criteria: * cognitive impairments as determined by cutoff scores (in points) of the Mini-Mental Status Examination according to education level reference; * any other neurological, musculoskeletal, cardiovascular, or respiratory disorders that could affect their ability to perform the tests; * used deep brain stimulation (DBS); * no access to the internet; * who do not have a caregiver or family member who can assist during the intervention sessions
Where this trial is running
Belo Horizonte, Minas Gerais
- Federal University of Minas Gerais — Belo Horizonte, Minas Gerais, Brazil (Recruiting)
Study contacts
- Principal investigator: Christina CM Faria, Ph.D. — Federal University of Minas Gerais
- Study coordinator: Christina CM Faria, Ph.D.
- Email: cdcmf@ufmg.br
- Phone: +55 (31) 34097448
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.