Home-based exercise program for endometrial cancer survivors in rural areas

RISE: Remote Intervention for Strength Training in Endometrial Cancer

Not applicable Interventional Mayo Clinic · NCT06213571

This study tests a home-based exercise program to see if it can help endometrial cancer survivors in rural areas feel better and improve their physical health.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages50 Years and up
SexFemale
SponsorMayo Clinic Academic / other
Locations1 site (Rochester, Minnesota)
Trial IDNCT06213571 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates a remote home-based exercise program designed to improve the quality of life for endometrial cancer survivors living in rural areas. The program includes resistance band and body weight exercises, along with educational materials and weekly coaching sessions over a 10-week period. The study aims to assess the recruitment, retention, and acceptability of this intervention, as well as its effectiveness on physical functioning in participants. By addressing barriers to exercise access, the trial seeks to provide a scalable solution for underserved populations.

Who should consider this trial

Good fit: Ideal candidates are adults aged 50 and older who are survivors of early stage, low risk endometrial cancer and reside in rural areas.

Not a fit: Patients with severe mobility impairments or those who do not speak English may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could enhance the quality of life and physical functioning for endometrial cancer survivors in rural areas.

How similar studies have performed: Other studies have shown promise in using remote exercise interventions for cancer survivors, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 50+
* Stage IA-IB endometrial cancer
* Grade 1-2 disease
* No recurrence documented
* Internet access
* Access to a remote device with a camera such as a computer, smartphone or tablet
* \> 1 year but less than 5 years from surgery
* Primary residence in rural-urban commuting area (RUCA) (rural-urban commuting area) codes 4.0 through 10.0 or of American Indian, Alaskan Native, Black or Hispanic background

Exclusion Criteria:

* Paraplegia/hemiplegia
* No English speaking

Where this trial is running

Rochester, Minnesota

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions FIGO Grade 1 Endometrial Endometrioid AdenocarcinomaFIGO Grade 2 Endometrial Endometrioid AdenocarcinomaStage IA Uterine Corpus Cancer AJCC V8Stage IB Uterine Corpus Cancer AJCC V8
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.