Clinical trial Recruiting at 3 sites Interventional

Home-based digital prism therapy for left-side spatial neglect

Official title: Feasibility and Effectiveness of a New Computerized Treatment Protocol for Spatial Neglect Post Stroke During Inpatient and Outpatient Rehabilitation

Run by Nova Scotia Health Authority · NCT05595668 · Data updated 2026-11-12

This trial will test whether a game-like prism adaptation program delivered on an iPad plus prism goggles can help people with spatial neglect after a right-hemisphere stroke, both in hospital and at home.

Quick facts

Study typeInterventional
SexAll
Enrollment80 (estimated)
SponsorNova Scotia Health Authority
Academic / other
Locations4 sites (Bedford, Nova Scotia and 3 other locations)
StatusRecruiting
StartedSeptember 15, 2023
Main results expectedNovember 2026
Study endsNovember 2026
Registry record updatedJuly 30, 2025
Trial IDNCT05595668 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults who had a right-hemisphere stroke, have mild to severe spatial neglect, are medically stable, can see and point to targets on a screen, and live within about two hours of Halifax are ideal candidates.

Probably not a fit

Patients with other neurological disorders (for example dementia, multiple sclerosis, or epilepsy), severe vision or motor impairments that prevent screen pointing, or who live outside the regional catchment area may not benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Investigators will run a randomized, controlled, multi-site trial comparing a gamified prism adaptation protocol (Peg-the-Mole) delivered on an iPad with a placebo control, using prism goggles as part of the intervention. Participants will receive the intervention during inpatient care and continue sessions at home, with the protocol designed to allow unsupervised use outside the clinic. Outcomes include short- and longer-term changes in neglect symptoms and measures of daily function, as well as feasibility and adherence to the home program. The study uses standard clinical inclusion/exclusion criteria and is conducted at Nova Scotia Health facilities near Halifax.

Why it matters

Potential benefit: If successful, this could reduce neglect symptoms and improve independence in daily activities by providing an easy-to-use, home-deliverable therapy.

How similar studies have gone: Prism adaptation has shown promising but mixed benefits for spatial neglect in prior research, while the gamified, at-home iPad delivery approach is newer and less well tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Have experienced a right hemisphere stroke (confirmed by a clinician)
2. Experience mild to severe symptoms of neglect
3. Be willing and able to consent to participate
4. Be medically stable
5. Have self-reported normal to corrected-to-normal vision
6. Be able to point to targets presented on a computer screen
7. Live within a two-hour radius of Halifax

Exclusion Criteria:

Other existing neurological disorders (e.g., dementia, multiple sclerosis, epilepsy).

Where it's running

  • Nova Scotia Health Early Supported Stroke Discharge Team
    Bedford, Nova Scotia, Canada
    Recruiting
  • Nova Scotia Rehabilitation and Arthritis Centre
    Halifax, Nova Scotia, Canada
    Recruiting
  • Valley Regional Hospital
    Kentville, Nova Scotia, Canada
    Recruiting
  • Nova Scotia Rehabilitation and Arthritis Centre (NSRAC)
    Halifax, Nova Scotia, Canada
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.