Home-based digital prism therapy for left-side spatial neglect
Feasibility and Effectiveness of a New Computerized Treatment Protocol for Spatial Neglect Post Stroke During Inpatient and Outpatient Rehabilitation
This trial will test whether a game-like prism adaptation program delivered on an iPad plus prism goggles can help people with spatial neglect after a right-hemisphere stroke, both in hospital and at home.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Sex | All |
| Sponsor | Nova Scotia Health Authority Academic / other |
| Locations | 4 sites (Bedford, Nova Scotia and 3 other locations) |
| Trial ID | NCT05595668 on ClinicalTrials.gov |
What this trial studies
Investigators will run a randomized, controlled, multi-site trial comparing a gamified prism adaptation protocol (Peg-the-Mole) delivered on an iPad with a placebo control, using prism goggles as part of the intervention. Participants will receive the intervention during inpatient care and continue sessions at home, with the protocol designed to allow unsupervised use outside the clinic. Outcomes include short- and longer-term changes in neglect symptoms and measures of daily function, as well as feasibility and adherence to the home program. The study uses standard clinical inclusion/exclusion criteria and is conducted at Nova Scotia Health facilities near Halifax.
Who should consider this trial
Good fit: Adults who had a right-hemisphere stroke, have mild to severe spatial neglect, are medically stable, can see and point to targets on a screen, and live within about two hours of Halifax are ideal candidates.
Not a fit: Patients with other neurological disorders (for example dementia, multiple sclerosis, or epilepsy), severe vision or motor impairments that prevent screen pointing, or who live outside the regional catchment area may not benefit or be eligible.
Why it matters
Potential benefit: If successful, this could reduce neglect symptoms and improve independence in daily activities by providing an easy-to-use, home-deliverable therapy.
How similar studies have performed: Prism adaptation has shown promising but mixed benefits for spatial neglect in prior research, while the gamified, at-home iPad delivery approach is newer and less well tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Have experienced a right hemisphere stroke (confirmed by a clinician) 2. Experience mild to severe symptoms of neglect 3. Be willing and able to consent to participate 4. Be medically stable 5. Have self-reported normal to corrected-to-normal vision 6. Be able to point to targets presented on a computer screen 7. Live within a two-hour radius of Halifax Exclusion Criteria: Other existing neurological disorders (e.g., dementia, multiple sclerosis, epilepsy).
Where this trial is running
Bedford, Nova Scotia and 3 other locations
- Nova Scotia Health Early Supported Stroke Discharge Team — Bedford, Nova Scotia, Canada (Recruiting)
- Nova Scotia Rehabilitation and Arthritis Centre (NSRAC) — Halifax, Nova Scotia, Canada (Not_yet_recruiting)
- Nova Scotia Rehabilitation and Arthritis Centre — Halifax, Nova Scotia, Canada (Recruiting)
- Valley Regional Hospital — Kentville, Nova Scotia, Canada (Recruiting)
Study contacts
- Study coordinator: Anne Sophie Champod, PhD
- Email: anne.champod@acadiau.ca
- Phone: 9028176871
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.