Home-based cognitive strategy training to support daily living after chronic stroke

Feasibility of Home-based Cognitive Strategy Training for Independence of Activities of Daily Living in Adults With Chronic Stroke

NA · University Hospital, Toulouse · NCT07084025

This pilot tests whether a home-delivered cognitive strategy program (PRPP-I) can help adults with chronic stroke become more independent in daily activities and improve quality of life.

Quick facts

PhaseNA
Study typeInterventional
Enrollment18 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital, Toulouse (other)
Locations1 site (Toulouse)
Trial IDNCT07084025 on ClinicalTrials.gov

What this trial studies

This pilot interventional study delivers the Perceive, Recall, Plan and Perform-Intervention (PRPP-I) protocol as task-based cognitive strategy training during real-life activities in participants' homes. It targets adults more than six months after ischemic or hemorrhagic stroke with mild to moderate cognitive impairment measured by the MoCA. The study will report feasibility outcomes (acceptability, adherence, and practicality of home delivery) and preliminary effectiveness on functional cognitive strategy use, independence in activities of daily living, quality of life, and caregiver burden. Participants receive individualized training during everyday tasks with outcome measures collected before and after the intervention.

Who should consider this trial

Good fit: Adults aged 18 or older who are at least six months post-ischemic or hemorrhagic stroke, live in a home or community setting, have a non-professional caregiver, and show mild to moderate cognitive impairment on the MoCA.

Not a fit: People with severe cognitive impairment (MoCA <18), severe aphasia, other non-stroke neurological diseases, or major psychiatric disorders are unlikely to benefit from this protocol.

Why it matters

Potential benefit: If successful, the program could increase independence in daily activities and reduce caregiver burden for people living with chronic stroke.

How similar studies have performed: Some task-based cognitive strategy programs have shown improvements in daily function, but home-based delivery of the PRPP-I protocol is relatively novel and mainly untested in large trials.

Eligibility criteria

Show full inclusion / exclusion criteria
Patient's Main Eligibility criteria:

* Adult over 18 years of age;
* cognitive deficits (or Acquired Brain Injury) diagnosed due to ischemic or hemorrhagic, hemispheric or brainstem stroke, confirmed by brain imaging longer than 6 months;
* Patient with mild (\<26/30 or \<25/30 for patients aged 71-85 yr) or moderate (\[18-25\]/30) cognitive impairment, measured by the Montreal Cognitive Assessment test ;
* adults living in a home or community-based setting;
* Patient with a non-professional caregiver;

Patient's Main Exclusion criteria

* Neurological pathology other than stroke or psychiatric disorder;
* Significant cognitive impairment, according to MoCA score \<18/30;
* Patient with severe aphasia, Boston Diagnostic Aphasia Examination score \>2

Where this trial is running

Toulouse

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stroke, Cerebrovascular Disorders, Cognitive strategy training, Task-based, Ecological, Performance, Activities of Daily Living

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.