High-resolution retinal imaging for patients with inherited retinal degenerations

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the structure and function of the retina in patients with inherited retinal degenerations using advanced imaging techniques such as the Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO) and Optical Coherence Tomography (OCT). By correlating high-resolution images with standard vision measures, the study seeks to enhance understanding of vision loss mechanisms in conditions like retinitis pigmentosa and cone-rod dystrophy. The research will also explore the functionality of individual photoreceptors through a novel technique called microperimetry. Ultimately, the findings could provide valuable insights into the progression of retinal diseases and potential future therapeutic approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects must speak and understand English
* Subjects must have pupils that dilate to at least 6 millimeters diameter.
* Subjects must be willing to travel to University of California (UC) Berkeley.
* Subjects are financially responsible for their travel to the San Francisco area if they are not San Francisco residents.

Exclusion Criteria:

* Cataract
* Irregular corneal astigmatism (keratoconus)
* Prior refractive surgery

Where it's running

• Department of Ophthalmology Retinal Degenerations Clinic, UCSF
  San Francisco, California, United States Recruiting

Study contacts

• Principal investigator: Jacque L. Duncan, M.D. — University of California, San Francisco
• Study coordinator: Jacque L. Duncan, M.D.
• Email: jacque.duncan@ucsf.edu
• Phone: 415-514-4241

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.