High-resolution MRI imaging for patients with atrial fibrillation before ablation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study involves patients with symptomatic paroxysmal or persistent atrial fibrillation who are undergoing a clinically indicated ablation procedure using FIRM mapping. Participants will receive high-resolution MRI scans with gadolinium-based contrast to create detailed 3D images of the atria before the procedure. The study aims to correlate fibrotic regions in the heart with the sites targeted for ablation based on FIRM mapping. Data will be collected before, during, and after the ablation procedure to enhance understanding of the disease state and improve treatment outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with symptomatic paroxysmal or persistent atrial fibrillation undergoing clinically-indicated ablation procedure employing FIRM mapping with pre-operative MRI.
2. Subjects must be at least 18 years of age.

Exclusion Criteria:

1. LAA thrombus present on pre-procedure TEE
2. Unable to undergo MRI imaging
3. Unable to receive gadolinium contrast.

Where it's running

• Ohio State University
  Columbus, Ohio, United States Recruiting

Study contacts

• Study coordinator: Adrianne Miller, RN
• Email: Adrianne.Miller@osumc.edu
• Phone: 614-685-4394

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.