High resolution anal examination for HPV and anal cancer detection
High Resolution Anuscopy Study
This study is testing how well high-resolution anal exams can help find high-risk HPV and anal cancer in people who are more likely to have these issues.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universitair Ziekenhuis Brussel Academic / other |
| Locations | 1 site (Jette) |
| Trial ID | NCT06697964 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on individuals who have undergone high-resolution anoscopy (HRA) to screen for high-risk human papillomavirus (HPV) and anal squamous cell carcinoma (SCC). It aims to collect and analyze data related to HPV infection and its link to anal pathology, particularly in high-risk populations. The study will utilize anal swabs for cytology and HPV detection, with referrals for HRA recommended for those with abnormal results. By examining this data, the researchers hope to answer critical clinical questions and enhance understanding of anal cancer prevention and treatment.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 18 and older who have undergone HRA or are referred for HRA at UZ Brussel and can communicate in French, Dutch, or English.
Not a fit: Patients who do not meet the eligibility criteria or those who have not undergone HRA may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved screening and early detection methods for anal cancer, potentially saving lives.
How similar studies have performed: While the approach of using HRA for screening is established, this study aims to deepen understanding through comprehensive data analysis, making it a valuable addition to existing research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients who have undergone HRA and all future patients referred for HRA in UZ Brussel * 18 years or older * Understands and able to speak and write in French, Dutch or English Exclusion Criteria: * None
Where this trial is running
Jette
- UZ Brussel — Jette, Belgium (Recruiting)
Study contacts
- Study coordinator: Magali Surmont
- Email: magali.surmont@uzbrussel.be
- Phone: +32 2 477
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.