Clinical trial Recruiting at 1 site Observational Ages 18 and up

High resolution anal examination for HPV and anal cancer detection

Official title: High Resolution Anuscopy Study

Run by Universitair Ziekenhuis Brussel · NCT06697964 · Data updated 2026-11-12

This study is testing how well high-resolution anal exams can help find high-risk HPV and anal cancer in people who are more likely to have these issues.

More Human Papilloma Virus trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorUniversitair Ziekenhuis Brussel
Academic / other
Locations1 site (Jette)
StatusRecruiting
StartedAugust 8, 2024
Main results expectedJuly 2029
Study endsJuly 2029
Registry record updatedFebruary 19, 2025
Trial IDNCT06697964 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals aged 18 and older who have undergone HRA or are referred for HRA at UZ Brussel and can communicate in French, Dutch, or English.

Probably not a fit

Patients who do not meet the eligibility criteria or those who have not undergone HRA may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on individuals who have undergone high-resolution anoscopy (HRA) to screen for high-risk human papillomavirus (HPV) and anal squamous cell carcinoma (SCC). It aims to collect and analyze data related to HPV infection and its link to anal pathology, particularly in high-risk populations. The study will utilize anal swabs for cytology and HPV detection, with referrals for HRA recommended for those with abnormal results. By examining this data, the researchers hope to answer critical clinical questions and enhance understanding of anal cancer prevention and treatment.

Why it matters

Potential benefit: If successful, this study could lead to improved screening and early detection methods for anal cancer, potentially saving lives.

How similar studies have gone: While the approach of using HRA for screening is established, this study aims to deepen understanding through comprehensive data analysis, making it a valuable addition to existing research.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients who have undergone HRA and all future patients referred for HRA in UZ Brussel
* 18 years or older
* Understands and able to speak and write in French, Dutch or English

Exclusion Criteria:

* None

Where it's running

  • UZ Brussel
    Jette, Belgium
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.