High resolution anal examination for HPV and anal cancer detection
Official title: High Resolution Anuscopy Study
Run by Universitair Ziekenhuis Brussel · NCT06697964 · Data updated 2026-11-12
This study is testing how well high-resolution anal exams can help find high-risk HPV and anal cancer in people who are more likely to have these issues.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Universitair Ziekenhuis Brussel Academic / other |
| Locations | 1 site (Jette) |
| Status | Recruiting |
| Started | August 8, 2024 |
| Main results expected | July 2029 |
| Study ends | July 2029 |
| Registry record updated | February 19, 2025 |
| Trial ID | NCT06697964 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 18 and older who have undergone HRA or are referred for HRA at UZ Brussel and can communicate in French, Dutch, or English.
✕Probably not a fit
Patients who do not meet the eligibility criteria or those who have not undergone HRA may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on individuals who have undergone high-resolution anoscopy (HRA) to screen for high-risk human papillomavirus (HPV) and anal squamous cell carcinoma (SCC). It aims to collect and analyze data related to HPV infection and its link to anal pathology, particularly in high-risk populations. The study will utilize anal swabs for cytology and HPV detection, with referrals for HRA recommended for those with abnormal results. By examining this data, the researchers hope to answer critical clinical questions and enhance understanding of anal cancer prevention and treatment.
Why it matters
Potential benefit: If successful, this study could lead to improved screening and early detection methods for anal cancer, potentially saving lives.
How similar studies have gone: While the approach of using HRA for screening is established, this study aims to deepen understanding through comprehensive data analysis, making it a valuable addition to existing research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients who have undergone HRA and all future patients referred for HRA in UZ Brussel * 18 years or older * Understands and able to speak and write in French, Dutch or English Exclusion Criteria: * None
Where it's running
-
UZ Brussel
Jette, Belgium Recruiting
Study contacts
- Study coordinator: Magali Surmont
- Email: magali.surmont@uzbrussel.be
- Phone: +32 2 477
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.