Clinical trial Recruiting at 1 site Observational Ages 18 and up

High-resolution 7 Tesla MRI of the cervical spine for adults with or without chronic back pain

Official title: 7 Tesla MRI Evaluation of the Spine

Run by Balgrist University Hospital · NCT04445584 · Data updated 2026-11-12

This uses a very-high-field 7 Tesla MRI to see how clearly nerve roots, ganglia, and the vertebral artery can be seen in adults with chronic back pain or in people without symptoms.

More Magnetic Resonance Imaging trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment600 (estimated)
SponsorBalgrist University Hospital
Academic / other
Locations1 site (Zurich, Canton of Zurich)
StatusRecruiting
StartedJune 1, 2020
Main results expectedFebruary 1, 2022
Study endsSeptember 30, 2027
Registry record updatedJuly 8, 2026
Trial IDNCT04445584 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 18 who can give informed consent, either have chronic back pain lasting more than two months or are asymptomatic volunteers, and have no prior spine surgery, spinal tumor, pregnancy/breastfeeding, or MRI contraindications.

Probably not a fit

People with prior spine surgery, spinal tumors, pregnancy or breastfeeding, or any MRI contraindication are not eligible and therefore would not receive benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational imaging project acquires high-resolution 7T MRI scans of the cervical spine to map fine anatomic details. Scans focus on differentiating nerve roots and ganglia from surrounding tissues within the foramina and on visualizing the vertebral artery's relation to neural structures. The protocol includes adults over 18 with chronic back pain (>2 months) as well as asymptomatic volunteers and excludes those with prior spine surgery, tumors, pregnancy or breastfeeding, or any MRI contraindications. All imaging is performed at Balgrist University Hospital in Zurich to build reference data on normal microanatomy and nerve dimensions.

Why it matters

Potential benefit: If successful, this could provide clearer images of cervical nerve structures and arteries, helping clinicians distinguish normal anatomy from disease and improving diagnostic confidence.

How similar studies have gone: High-field 7T MRI has shown superior anatomical detail in brain research and some spinal imaging reports, but routine use for precise cervical nerve root and ganglia measurements is still relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

* Informed consent as documented by signature (Appendix Informed Consent Form)
* \>18 years old
* Patients presenting chronic back pain (\> 2 months) without recent trauma, previous MRI (1,5 or 3T) for clinicals indications or asymptomatic individuals (for depicting normal microanatomy)

Exclusion criteria:

* previous surgery
* tumor patients
* pregnancy or breast feeding
* any MRI contra-indications
* any MRI contra-indications

Where it's running

  • Balgrist University Hospital
    Zurich, Canton of Zurich, Switzerland
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.