High-resolution 7 Tesla MRI of the cervical spine for adults with or without chronic back pain
Official title: 7 Tesla MRI Evaluation of the Spine
Run by Balgrist University Hospital · NCT04445584 · Data updated 2026-11-12
This uses a very-high-field 7 Tesla MRI to see how clearly nerve roots, ganglia, and the vertebral artery can be seen in adults with chronic back pain or in people without symptoms.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Balgrist University Hospital Academic / other |
| Locations | 1 site (Zurich, Canton of Zurich) |
| Status | Recruiting |
| Started | June 1, 2020 |
| Main results expected | February 1, 2022 |
| Study ends | September 30, 2027 |
| Registry record updated | July 8, 2026 |
| Trial ID | NCT04445584 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 who can give informed consent, either have chronic back pain lasting more than two months or are asymptomatic volunteers, and have no prior spine surgery, spinal tumor, pregnancy/breastfeeding, or MRI contraindications.
✕Probably not a fit
People with prior spine surgery, spinal tumors, pregnancy or breastfeeding, or any MRI contraindication are not eligible and therefore would not receive benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational imaging project acquires high-resolution 7T MRI scans of the cervical spine to map fine anatomic details. Scans focus on differentiating nerve roots and ganglia from surrounding tissues within the foramina and on visualizing the vertebral artery's relation to neural structures. The protocol includes adults over 18 with chronic back pain (>2 months) as well as asymptomatic volunteers and excludes those with prior spine surgery, tumors, pregnancy or breastfeeding, or any MRI contraindications. All imaging is performed at Balgrist University Hospital in Zurich to build reference data on normal microanatomy and nerve dimensions.
Why it matters
Potential benefit: If successful, this could provide clearer images of cervical nerve structures and arteries, helping clinicians distinguish normal anatomy from disease and improving diagnostic confidence.
How similar studies have gone: High-field 7T MRI has shown superior anatomical detail in brain research and some spinal imaging reports, but routine use for precise cervical nerve root and ganglia measurements is still relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * Informed consent as documented by signature (Appendix Informed Consent Form) * \>18 years old * Patients presenting chronic back pain (\> 2 months) without recent trauma, previous MRI (1,5 or 3T) for clinicals indications or asymptomatic individuals (for depicting normal microanatomy) Exclusion criteria: * previous surgery * tumor patients * pregnancy or breast feeding * any MRI contra-indications * any MRI contra-indications
Where it's running
-
Balgrist University Hospital
Zurich, Canton of Zurich, Switzerland Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.