High-protein, high-fiber pre-fast meal effects on fullness and blood sugar during fasting
Official title: Effect of a High-Protein, High-Fiber Pre-Fast Meal on Satiety and Glycemic Profiles During Fasting: A Randomized Crossover Study
Run by King Faisal University · NCT07447505 · Data updated 2026-11-12
This test sees if eating a high-protein, high-fiber meal before a fasting period helps healthy adults feel fuller and keep blood sugar steadier than a low-protein, low-fiber meal.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 38 (estimated) |
| Sponsor | King Faisal University Academic / other |
| Locations | 1 site (Al-Ahsa, Eastern Province) |
| Status | Recruiting |
| Started | February 23, 2026 |
| Main results expected | March 23, 2026 |
| Study ends | March 23, 2026 |
| Registry record updated | March 12, 2026 |
| Trial ID | NCT07447505 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy adults aged 18 and older who can fast, wear a continuous glucose monitor, and are not pregnant, lactating, diabetic, or allergic to the meal components are ideal candidates.
✕Probably not a fit
People with diagnosed diabetes or other metabolic diseases, those taking medications that affect glucose or appetite, pregnant or breastfeeding individuals, or anyone allergic to oats, dairy, peanuts, or nuts are unlikely to benefit and are excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In a randomized crossover design, healthy adults will complete two pre-fast meal conditions in random order: a standardized high-protein, high-fiber meal (oats, Greek yogurt, peanut butter, dried cranberries, almonds) and a low-protein, low-fiber meal guided by written instructions. Each condition is followed for two consecutive days with a three-day washout between conditions to limit carryover effects. Subjective appetite sensations will be recorded at preset times during the fasting day using visual analogue-type scales, while continuous glucose monitoring (CGM) will capture glycemic profiles throughout each condition. Exploratory analyses will examine temporal associations between CGM-derived glucose dynamics and reported appetite sensations.
Why it matters
Potential benefit: If successful, this could provide a simple mealtime strategy to increase satiety and reduce blood sugar swings during fasting, making fasting periods more comfortable and metabolically stable for healthy adults.
How similar studies have gone: Previous short-term studies of higher-protein and higher-fiber meals have tended to reduce postprandial glucose spikes and increase feelings of fullness, so this study applies those concepts specifically to the pre-fast context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 years and older * Willingness to comply with study procedures, including fasting and continuous glucose monitoring * Ability to provide informed consent Exclusion Criteria: * Diagnosed diabetes mellitus or known metabolic disease * History of cardiovascular, gastrointestinal, or endocrine disorders that may affect study outcomes * Use of medications known to affect glucose metabolism or appetite * Pregnancy or lactation * Known allergy or intolerance to any study meal components (oats, dairy, peanuts, nuts, cranberries)
Where it's running
-
King Faisal University
Al-Ahsa, Eastern Province, Saudi Arabia Recruiting
Study contacts
- Study coordinator: Wafa Alotaibi
- Email: Walotaibi@kfu.edu.sa
- Phone: +966500358622
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.