High-intensity therapy program for arm recovery after chronic stroke

intenSive UpPer Extremity Recovery Program for Chronic Stroke (SUPER)

Not applicable Interventional The University of Texas Health Science Center, Houston · NCT05689502

This study tests a tough therapy program for people who have had a stroke to see if it can help them recover better and improve their daily life.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment9 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorThe University of Texas Health Science Center, Houston Academic / other
Locations1 site (Houston, Texas)
Trial IDNCT05689502 on ClinicalTrials.gov

What this trial studies

This study investigates the feasibility and effects of a high-quality, high-dose, high-intensity upper extremity therapy program for individuals who have experienced a chronic stroke. Participants will undergo intensive therapy aimed at improving functional outcomes, motor impairment, and overall quality of life. The program is designed for those who can tolerate six hours of therapy per day and have specific eligibility criteria related to their stroke history and current physical capabilities.

Who should consider this trial

Good fit: Ideal candidates are individuals who have had a single stroke event at least six months prior, with a Fugl-Meyer upper extremity score between 20 and 45.

Not a fit: Patients with prior arm injuries, significant arm pain, advanced dementia, or medical instability may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly enhance arm recovery and improve the quality of life for patients with chronic stroke.

How similar studies have performed: Other studies have shown promising results with high-intensity rehabilitation approaches for stroke recovery, indicating potential for success in this novel program.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Single qualifying stroke event as confirmed by CT or MRI
* At least 6 months post stroke
* Fugl-Meyer upper extremity (UE) score of 20-45
* Able to follow written instructions
* Able to tolerate 6 hours of therapy a day

Exclusion Criteria:

* Prior arm injury impacting available passive or active range of motion or significant arm pain with movement
* Active drug or alcohol abuse
* Diagnosed with advanced dementia
* Pre-stroke baseline mRS\>3
* History of clinically significant ischemic or hemorrhagic stroke resulting in prior arm weakness in the same territory as the index stroke
* Medical instability assessed by the treating stroke physician to participate to the study.

Where this trial is running

Houston, Texas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic StrokeRehabilitationArm recoveryHigh intensity therapyOccupational therapyPhysical therapy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.