High-intensity interval training for wheelchair users with spinal muscular atrophy
High-intensity Interval Training in Patients With Spinal Muscular Atrophy
This study is testing if high-intensity interval training can help improve movement and quality of life for wheelchair users with spinal muscular atrophy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 15 Years and up |
| Sex | All |
| Sponsor | Rigshospitalet, Denmark Academic / other |
| Locations | 1 site (Copenhagen) |
| Trial ID | NCT06368076 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of high-intensity interval training (HIIT) on patients with spinal muscular atrophy (SMA) who are wheelchair users. It aims to determine if HIIT can serve as a viable exercise modality for these patients and to assess its impact on their motor function and associated symptoms such as pain and reduced quality of life. Participants will undergo an 8-week control period followed by a training regimen of 10 minutes of HIIT, five times a week. The study will evaluate changes in symptoms and overall well-being before and after the intervention.
Who should consider this trial
Good fit: Ideal candidates are individuals over 15 years old diagnosed with spinal muscular atrophy who are wheelchair users.
Not a fit: Patients with competing disorders, other muscle disorders, or those unable to use the cycle ergometer due to contractures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the quality of life and alleviate symptoms for patients with spinal muscular atrophy.
How similar studies have performed: Previous research has shown that high-intensity interval training is well tolerated in patients with similar neuromuscular conditions, suggesting potential for success in this study.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Spinal muscular atrophy * Age: over 15 years Exclusion Criteria: * Competing disorders (as arthritis) or other muscle disorders as well as heart- or lung related issues. * Current psychiatric treatment * Unable to use the cycle ergometer due to contractures
Where this trial is running
Copenhagen
- Rigshospitalet — Copenhagen, Denmark (Recruiting)
Study contacts
- Principal investigator: John Vissing, prof. MD — Rigshospitalet, Denmark
- Study coordinator: Sophia Frølich, stud.med
- Email: sophia.vera.froelich.01@regionh.dk
- Phone: + 45 3545 3561
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.