Clinical trial Recruiting at 1 site Interventional Ages 50 to 80

High-intensity interval training for stroke rehabilitation

Official title: Powering Up Stroke Rehabilitation Through High-Intensity Interval Training

Run by The Hong Kong Polytechnic University · NCT06554665 · Data updated 2026-11-12

This study is testing if high-intensity interval training can help improve muscle strength in people who have had a stroke compared to moderate exercise and stretching.

Quick facts

Study typeInterventional
Ages50 Years to 80 Years
SexAll
Enrollment66 (estimated)
SponsorThe Hong Kong Polytechnic University
Academic / other
Locations1 site (Kowloon)
StatusRecruiting
StartedAugust 20, 2024
Main results expectedAugust 5, 2027
Study endsAugust 5, 2027
Registry record updatedSeptember 21, 2026
Trial IDNCT06554665 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are men and postmenopausal women aged 50-80 who are 1-5 years post-stroke and can walk independently.

Probably not a fit

Patients with other neurological conditions, significant organ diseases, or those currently undergoing stroke rehabilitation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of high-intensity interval training (HIIT) on musculoskeletal fitness in chronic stroke survivors. Participants will be randomly assigned to one of three groups: HIIT, moderate-intensity continuous training (MICT), or a stretching group. Each group will attend training sessions three times a week for 12 weeks, with assessments conducted at various intervals to measure muscle power and other outcomes. The study aims to determine if HIIT can significantly enhance muscle power compared to MICT.

Why it matters

Potential benefit: If successful, this approach could lead to improved muscle power and rehabilitation outcomes for chronic stroke survivors.

How similar studies have gone: Other studies have shown positive outcomes with high-intensity interval training in various populations, suggesting potential success in this novel application for stroke rehabilitation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

* Men and postmenopausal women aged 50-80 years
* 1-5 years following the first-ever stroke confirmed by magnetic resonance imaging or computed tomography
* Able to walk 10 meters independently with or without a walking aid
* Class I or II according to the New York Heart Association Functional Classification (no limitation or slight limitation of physical activity due to symptoms during ordinary physical activity)

Exclusion criteria:

* Presence of other neurological comorbidities, significant liver or renal diseases, thyroid or parathyroid diseases, rheumatoid arthritis, or a fracture within the past 6 months
* Undergoing osteoporosis treatments within the past 3 years, use of oral corticosteroids for more than 3 months within the past year, or botulinum toxin injections in the paretic lower limb within the past 6 months
* Participation in ongoing stroke rehabilitation services or structured exercise programme
* Cognitive or communication issues that could limit the ability to follow instructions
* Contraindications to HIIT, graded exercise testing, or failure to pass medical clearance from a specialist

Where it's running

  • The Hong Kong Polytechnic University
    Kowloon, Hong Kong
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.