High-intensity interval training for stroke rehabilitation
Official title: Powering Up Stroke Rehabilitation Through High-Intensity Interval Training
Run by The Hong Kong Polytechnic University · NCT06554665 · Data updated 2026-11-12
This study is testing if high-intensity interval training can help improve muscle strength in people who have had a stroke compared to moderate exercise and stretching.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years to 80 Years |
| Sex | All |
| Enrollment | 66 (estimated) |
| Sponsor | The Hong Kong Polytechnic University Academic / other |
| Locations | 1 site (Kowloon) |
| Status | Recruiting |
| Started | August 20, 2024 |
| Main results expected | August 5, 2027 |
| Study ends | August 5, 2027 |
| Registry record updated | September 21, 2026 |
| Trial ID | NCT06554665 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are men and postmenopausal women aged 50-80 who are 1-5 years post-stroke and can walk independently.
✕Probably not a fit
Patients with other neurological conditions, significant organ diseases, or those currently undergoing stroke rehabilitation may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effects of high-intensity interval training (HIIT) on musculoskeletal fitness in chronic stroke survivors. Participants will be randomly assigned to one of three groups: HIIT, moderate-intensity continuous training (MICT), or a stretching group. Each group will attend training sessions three times a week for 12 weeks, with assessments conducted at various intervals to measure muscle power and other outcomes. The study aims to determine if HIIT can significantly enhance muscle power compared to MICT.
Why it matters
Potential benefit: If successful, this approach could lead to improved muscle power and rehabilitation outcomes for chronic stroke survivors.
How similar studies have gone: Other studies have shown positive outcomes with high-intensity interval training in various populations, suggesting potential success in this novel application for stroke rehabilitation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * Men and postmenopausal women aged 50-80 years * 1-5 years following the first-ever stroke confirmed by magnetic resonance imaging or computed tomography * Able to walk 10 meters independently with or without a walking aid * Class I or II according to the New York Heart Association Functional Classification (no limitation or slight limitation of physical activity due to symptoms during ordinary physical activity) Exclusion criteria: * Presence of other neurological comorbidities, significant liver or renal diseases, thyroid or parathyroid diseases, rheumatoid arthritis, or a fracture within the past 6 months * Undergoing osteoporosis treatments within the past 3 years, use of oral corticosteroids for more than 3 months within the past year, or botulinum toxin injections in the paretic lower limb within the past 6 months * Participation in ongoing stroke rehabilitation services or structured exercise programme * Cognitive or communication issues that could limit the ability to follow instructions * Contraindications to HIIT, graded exercise testing, or failure to pass medical clearance from a specialist
Where it's running
-
The Hong Kong Polytechnic University
Kowloon, Hong Kong Recruiting
Study contacts
- Study coordinator: Chen Xu, PhD student
- Email: rschen.xu@connect.polyu.hk
- Phone: 00000000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
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Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
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AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
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Web-based therapy using action observation and mirror therapy for arm weakness after stroke
This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.
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Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
-
Dual-task balance training plus computer-based cognitive training after stroke
In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.