High-intensity exercise program for people with Parkinson's disease

Comparison of High-intensity Interval Circuit Training With Upper Extremity and Lower Extremity Training Versus Lower Extremity Training Alone in People With Parkinson Disease

Not applicable Interventional Pacific Northwest University of Health Sciences · NCT06576817

This study is testing whether a high-intensity exercise program that includes both upper and lower body workouts can help people with Parkinson's disease improve their balance, speed, and overall quality of life compared to just lower body exercises.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment64 (estimated)
SexAll
SponsorPacific Northwest University of Health Sciences Academic / other
Locations1 site (Yakima, Washington)
Trial IDNCT06576817 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effects of high-intensity interval circuit training that includes both lower and upper extremity exercises versus lower extremity exercises alone in individuals with Parkinson's disease. Participants will be randomly assigned to one of two groups and will attend eight exercise classes designed to improve reaction time, balance, gait speed, and overall quality of life. The study will involve baseline assessments, followed by the exercise intervention, and concluding with post-intervention evaluations to measure outcomes. The exercise circuit will consist of various stations targeting different functional aspects, ensuring a comprehensive approach to physical activity.

Who should consider this trial

Good fit: Ideal candidates include individuals diagnosed with Parkinson's disease who can walk independently and have a Hoehn and Yahr level of 1 to 3.

Not a fit: Patients with other neurological diseases, severe cardiovascular issues, or significant musculoskeletal problems may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance physical function and quality of life for patients with Parkinson's disease.

How similar studies have performed: Previous studies have shown positive outcomes with exercise interventions in Parkinson's disease, suggesting this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* diagnosis of Parkinson's disease
* Hoehn and Yahr level of 1 to 3
* ability to walk independently with or without an assistive device
* obtain medical clearance to participate in moderate or vigorous exercise.

Exclusion Criteria:

* diagnosis of any neurological disease other than PD (including but not limited to stroke, dementia, and multiple sclerosis; mild cognitive impairment is not excluded)
* bone instability (non-consolidated fractures, unstable spinal column, severe osteoporosis)
* muscle or ligament tears
* uncontrolled hypertension
* uncontrolled diabetes
* severe cardiovascular disease that impairs walking or exercise
* a major change in medication during the study training period (pre-test to post-test)

Where this trial is running

Yakima, Washington

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Parkinson Diseaseexercise
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.