High-intensity circuit training plus home telerehab to improve walking and balance in people with mild-to-moderate MS

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants complete ten one-hour high-intensity, task-oriented circuit training sessions in a hospital setting focusing on walking, stepping, supine-to-stand transitions, and general mobility. After the in-person program, participants follow three months of asynchronous telerehabilitation without real-time physiotherapist supervision to try to maintain gains. The study is a feasibility interventional protocol aimed at safety, tolerability, and preliminary signals of benefit on gait and balance. Outcomes will include measures of gait and balance functional capacity and the durability of any improvements over a six-month period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of primary or secondary progressive multiple sclerosis according to the McDonald criteria.
* Mini-Mental State Examination (MMSE) score \> 24.
* Expanded Disability Status Scale (EDSS) score ≤ 6.

Exclusion Criteria:

* Presence of other psychiatric or neurological disorders.
* Cardiopulmonary, renal, or liver diseases.
* Pregnancy.
* Modifications in drug treatment within the last 3 months.

Where it's running

• Ferrara University Hospital
  Ferrara, Fe, Italy Recruiting

Study contacts

• Study coordinator: Sofia Straudi, MD, PhD
• Email: sofia.straudi@unife.it
• Phone: +390532238720

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.