High-intensity aerobic and strength exercise for adults with chronic kidney disease on dialysis or conservative care

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with CKD (stages 1–5) who are either under conservative care or on chronic hemodialysis for at least three months will be randomized to a combined high-intensity aerobic plus resistance training program or to a control group receiving usual care. The intervention involves supervised high-intensity aerobic and strength sessions, while the control group continues standard management without the exercise program. Participants undergo a cardiopulmonary exercise test for safety screening, and those with severe cardiovascular disease, recent ischemic events, or anatomical limitations are excluded. The trial is run at a single private clinic in Peschiera del Garda, Verona, Italy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Signature of the informed consent
* Patients with CKD stage 1 to 5 under conservative treatment
* Patients undergoing chronic hemodialysis for at least 3 months
* Age ≥ 18

Exclusion Criteria:

* Severe cardiovascular disease (NYHA class IV or hypertension class III)
* TIA or myocardial ischemia within the last three months
* Anatomical limitations
* Health conditions detected during the stress test (CPET)

Where it's running

• Ospedale P. Pederzoli Casa di Cura Privata S.p.A.
  Peschiera del Garda, Verona, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.