High-frequency spinal cord stimulation for herpes zoster pain relief

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of high-frequency spinal cord stimulation (HF-SCS) in treating herpes zoster-associated neuralgia, a painful condition resulting from the reactivation of the varicella-zoster virus. The research focuses on patients who have not responded adequately to conventional treatments and examines the impact of HF-SCS on pain relief and quality of life. The methodology involves comparing HF-SCS with traditional low-frequency stimulation, assessing various parameters such as frequency, pulse width, and amplitude to optimize pain management. The study aims to provide insights into the mechanisms of pain modulation and the potential benefits of HF-SCS in this patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with inadequate response to non-surgical treatments such as pharmacotherapy;
2. Patients with major organ dysfunction intolerant to drug therapy;
3. Patients with systemic comorbidities (e.g., hypertension, diabetes mellitus);
4. Patients with moderate to severe pain intensity (Numerical Rating Scale \[NRS\] score ≥ 4).

Exclusion Criteria:

1. Patients with severe psychiatric disorders;
2. Patients with severe local or systemic infections at the puncture site;
3. Patients with severe coagulopathies (platelet count \< 80×10⁹/L during puncture) or those requiring uninterrupted anticoagulation therapy without bridging protocol;
4. Patients with end-stage organ failure who cannot maintain prone positioning or tolerate the procedure;
5. Patients with severe spinal stenosis, vertebral ankylosis, or scoliosis;
6. Patients with language barrier or impaired communication abilities.ion

Where it's running

• 149 Dalian Road, Huichuan District, Zunyi City, Guizhou Province
  Zunyi, Guizhou, China Recruiting

Study contacts

• Study coordinator: 梨 赵
• Email: 1287802477@qq.com
• Phone: +8615285410762

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.