High-frequency pulsed vacuum versus phacoemulsification for bilateral cataract surgery
Official title: "Comparative Study of High-frequency Pulsed Vacuum Technology Versus Phacoemulsification for Cataract Surgery
Run by Clinique Victor Pauchet · NCT07074431 · Data updated 2026-11-12
This trial will test a new high-frequency pulsed vacuum technique against standard phacoemulsification in adults who need cataract surgery in both eyes to see if recovery is faster and surgery is safer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Clinique Victor Pauchet Academic / other |
| Locations | 1 site (Amiens) |
| Status | Recruiting |
| Started | December 12, 2025 |
| Main results expected | April 2028 |
| Study ends | April 2028 |
| Registry record updated | October 5, 2026 |
| Trial ID | NCT07074431 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with bilateral cataracts graded 1 to 3 who are indicated for bilateral surgery, can read and understand French, and can give informed consent are ideal candidates.
✕Probably not a fit
Patients with cataract grade greater than 3, uveitic cataracts, glaucoma, other ocular comorbidities, unilateral or combined surgeries, or those unable to consent or read French are unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The study compares a novel high-frequency pulsed vacuum cataract ablation method with the widely used phacoemulsification technique in adults with bilateral grade 1–3 cataracts. The pulsed vacuum approach intermittently interrupts suction to create brief impact moments that dissect cataract material while aiming to preserve surrounding tissue and anterior chamber stability. Participants who meet eligibility will undergo cataract surgery and be followed for surgical outcomes, recovery speed, safety, and patient satisfaction. Key exclusions include advanced cataracts (> grade 3), uveitic cataract, glaucoma, other ocular comorbidities, inability to consent or complete questionnaires in French, and pregnancy.
Why it matters
Potential benefit: If successful, this approach could shorten recovery time and reduce intraoperative trauma and complications compared with standard phacoemulsification.
How similar studies have gone: Phacoemulsification is well established with strong evidence, while high-frequency pulsed vacuum is a novel technique with limited prior clinical data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patient * Patient with bilateral cataracts * Grade 1 to 3 cataracts * Indication for bilateral cataract surgery * Patient informed of the study and having given their written and signed informed consent * Patient affiliated with a social security scheme or beneficiary of such a scheme Exclusion Criteria: * Refusal of consent * Cataract grade \> 3 * Unilateral and/or combined cataract surgery * Uveitic cataract * Glaucoma * Patient with ocular comorbidity * Patient with cognitive impairment preventing them from responding to satisfaction questionnaires * Patient unable to read, write, or understand French * Pregnant or breastfeeding patient as defined in Article L1121-5 of the French Public Health Code * Vulnerable patient as defined in Article L1121-6 of the French Public Health Code * Adult patient under guardianship, curatorship, or legal protection * Patient unable to give personal consent
Where it's running
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Clinique Victor Pauchet
Amiens, France Recruiting
Study contacts
- Study coordinator: Aurélie DUSSAUSSOY, Clinical research associated
- Email: aurelie.dussaussoy@pauchet.com
- Phone: +33 3 22 33 74 78
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Comparison of Unity and Centurion phacoemulsification systems for bilateral cataract surgery
This test compares the Unity and Centurion phacoemulsification systems to see which uses less ultrasound time and cumulative dispersed energy in adults having sequential bilateral cataract surgery for nuclear sclerosis.
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Immediate versus delayed bilateral cataract surgery in France
This study will test whether doing cataract surgery on both eyes the same day is as safe and cost-effective as doing the two operations on separate days for adults in France with cataracts in both eyes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.