High flow oxygen methods for preoxygenation in young children during anesthesia induction
High Flow Oxygen in Preoxygenation During Rapid Sequence Induction in Infants and Small Children: Pilot Randomized Controlled Trial
This study tests which method of giving oxygen works best for young children during anesthesia induction, comparing face masks, high-flow nasal oxygen, or a mix of both.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | N/A to 6 Years |
| Sex | All |
| Sponsor | Brno University Hospital Academic / other |
| Locations | 1 site (Brno, South Moravian Region) |
| Trial ID | NCT05846919 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of different preoxygenation methods during rapid sequence induction (RSI) in infants and small children. Participants will be randomly assigned to receive preoxygenation via face-mask, high-flow nasal oxygen cannula (HFNOC), or a combination of both. The study will monitor vital signs, oxygen saturation, and safety outcomes during the induction process. The goal is to determine which method provides better oxygenation and safety during anesthesia induction in pediatric patients.
Who should consider this trial
Good fit: Ideal candidates for this study are pediatric patients who require rapid sequence induction for acute surgical procedures.
Not a fit: Patients who do not require rapid sequence induction for anesthesia induction will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the safety and effectiveness of anesthesia induction in infants and small children, reducing the risk of hypoxia and related complications.
How similar studies have performed: While there is ongoing research in pediatric anesthesia, this specific comparison of preoxygenation methods in young children during RSI is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pediatric patients indicated for rapid sequence induction * informed consent Exclusion Criteria: * decline to participate * rapid sequence induction not required for anesthesia induction
Where this trial is running
Brno, South Moravian Region
- Brno University Hospital — Brno, South Moravian Region, Czechia (Recruiting)
Study contacts
- Study coordinator: Dominik Fabian, MD
- Email: fabian.dominik@fnbrno.cz
- Phone: 532234695
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.