High Energy Laser Therapy for a Grade III A Lower-Limb Muscle Tear
Official title: Effects of High Intensity Laser Therapy In Lower Limb Muscle Injuries: a Randomized Controlled Study
Run by Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari · NCT06812611 · Data updated 2026-11-12
This study tests whether using high-energy laser therapy in addition to exercise helps people with a grade III A muscle tear in the legs recover faster.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 16 Years and up |
| Sex | All |
| Enrollment | 24 (estimated) |
| Sponsor | Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari Academic / other |
| Locations | 1 site (Bari) |
| Status | Recruiting |
| Started | December 1, 2025 |
| Main results expected | January 1, 2027 |
| Study ends | April 1, 2027 |
| Registry record updated | May 14, 2026 |
| Trial ID | NCT06812611 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates have a confirmed grade III A lower-limb muscle tear, are actively engaged in sports, and have no recent lower-limb injuries.
✕Probably not a fit
Individuals with contraindications to biostimulation, recent muscle injuries within 6 months, or prior knee/ankle instability may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Participants with a confirmed grade III A lower-limb muscle tear engage in a high-energy laser therapy plus exercise approach. The trial compares this biostimulation plus rehabilitation strategy to a standard exercise program to observe effects on pain, edema, and recovery of function. Outcomes will be measured with ultrasound confirmation of healing and patient-reported recovery milestones. The study aims to provide preliminary clinical evidence for the safety and potential benefit of high-energy laser therapy in sports-related muscle injuries.
Why it matters
Potential benefit: If successful, participants may experience faster pain relief and quicker return to sport.
How similar studies have gone: Evidence on high-energy laser therapy for muscle injuries is limited but prior biostimulation research suggests potential biological effects; results are preliminary.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * presence of a grade III A muscle lesion of the lower limbs, according to the Mueller-Wohlfart classification, confirmed by ultrasound examination and occurred during sporting activity at least 5 days before inclusion in the study; * no previous muscle injury in the last 6 months; * signing of the written informed consent for participation in the study. Exclusion Criteria: * previous muscle injuries or bone fractures of the lower limbs in the last 6 months; * knee instability due to previous rupture of the knee ligaments; • instability or previous sprain of the ankle; * active neoplastic or infectious diseases; * contraindications to biostimulation; * congenital anomalies of the lower limbs.
Where it's running
-
Policlinico di Bari
Bari, Italy Recruiting
Study contacts
- Study coordinator: Angela Notarnicola, M.D.Ph.D.
- Email: angelanotarnicola@yahoo.it
- Phone: 0805592938
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.