Hepatitis C care in housing: pharmacist, clinician, and navigator team helps residents
Official title: A Hybrid Implementation-Effectiveness Study of the Pharmacist, Physician, and Patient Navigator Collaborative Care Model (PPP-CCM) to Cure Hepatitis C Among Persons Who Use Drugs With Housing Insecurity
Run by University of Washington · NCT07667101 · Data updated 2026-11-12
We're testing a team-based approach to help adults living in supportive housing get faster access to hepatitis C medicines and care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 444 (estimated) |
| Sponsor | University of Washington Academic / other |
| Locations | 1 site (Seattle, Washington) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | June 2028 |
| Study ends | June 2029 |
| Registry record updated | June 24, 2026 |
| Trial ID | NCT07667101 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older who live in DESC’s PSH buildings, have a documented positive HCV test, and consent to share information to track care.
✕Probably not a fit
Individuals not seeking HCV treatment or not connected to the participating housing buildings may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pragmatic, cluster-randomized trial will involve 16 permanent supportive housing buildings in Seattle and King County. Half of the buildings will implement the PPP-CCM intervention for 12 months, while the other half provide usual care; after this period, all buildings will receive the PPP-CCM. All buildings offer point-of-care HCV screening for six months. Researchers will follow people who screen-positive for HCV with surveys and medical record reviews at baseline, 12 months, and 24 months to examine outcomes related to HCV care and treatment access.
Why it matters
Potential benefit: If successful, residents may experience faster access to hepatitis C treatment and improved linkage to care.
How similar studies have gone: Previous pragmatic implementations of care-coordination models in housing settings have shown potential to improve linkage to care, supporting exploration of PPP-CCM in this setting.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult ≥18 years of age * Currently a resident at one of DESC's PSH buildings at the time of study enrollment * Positive HCV test documented (screening antibody test or viral load test) * Provides release of information (ROI) to access community pharmacy electronic medical records (EHR) and/or other HCV treatment providers for information on HCV care during the study period between baseline visit and 24-month visit Exclusion Criteria: * Taking medications to treat HCV at the start of the study * Cognitive impairment (acute or chronic) resulting in inability to provide informed consent * Currently or impending incarceration * People who plan to leave the Seattle area within 24 months * Not English speaking * Behavioral risk posing safety concerns per discretion of research staff
Where it's running
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Harborview Medical Center
Seattle, Washington, United States Recruiting
Study contacts
- Principal investigator: Judith Tsui, MD, MPH — University of Washington
- Study coordinator: Devin N Kennedy
- Email: kennedev@uw.edu
- Phone: 206-744-1838
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.