Hepatitis B virus infection in children after liver transplantation
Clinical Follow-up Study on Hepatitis B Virus Infection After Liver Transplantation in Children
This study looks at how common hepatitis B virus infection is in children who have received liver transplants and what it means for their health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Sex | All |
| Sponsor | Children's Hospital of Chongqing Medical University Academic / other |
| Locations | 1 site (Chongqing, Chongqing) |
| Trial ID | NCT03865966 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the prevalence and implications of hepatitis B virus (HBV) infection in children who have undergone liver transplantation. Given the high rates of HBV infection in China, the study aims to understand how HBV can be transmitted through donor livers or reactivate in patients post-transplant due to immunosuppressive therapy. The research will involve monitoring children with end-stage liver disease who are receiving liver transplants to assess the risk and outcomes associated with HBV infection.
Who should consider this trial
Good fit: Ideal candidates for this study are children with end-stage liver disease who are scheduled to undergo liver transplantation.
Not a fit: Children who do not require liver transplantation or are unwilling to participate in the study may not receive any benefit.
Why it matters
Potential benefit: If successful, this study could improve the management and outcomes of liver transplantation in children by identifying and mitigating the risks associated with HBV infection.
How similar studies have performed: While there is existing literature on HBV infection in liver transplant patients, this specific observational approach in children is less common and may provide novel insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with end-stage liver disease who require liver transplantation Exclusion Criteria: * Children without liver transplantation refer to children; * Children who are unwilling to participate;
Where this trial is running
Chongqing, Chongqing
- Chongqing Children's Hospital of Chongqing Medical University — Chongqing, Chongqing, China (Recruiting)
Study contacts
- Principal investigator: Yao Zhao — Chongqing Children's Hospital of Chongqing Medical University
- Study coordinator: Yao Zhao
- Email: Zhaoy@cqmu.edu.cn
- Phone: +862363603083
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.