Helping young cancer survivors manage stress and build resilience

Promoting Resilience in Early Survivorship Among Adolescents and Young Adults With Cancer

NA · Dana-Farber Cancer Institute · NCT06038318

This study is testing a program that helps young cancer survivors manage stress and build resilience through coaching and education delivered via a mobile app or video.

Quick facts

PhaseNA
Study typeInterventional
Enrollment325 (estimated)
Ages12 Years to 25 Years
SexAll
SponsorDana-Farber Cancer Institute (other)
Locations2 sites (Boston, Massachusetts and 1 other locations)
Trial IDNCT06038318 on ClinicalTrials.gov

What this trial studies

This study aims to identify effective methods for assisting adolescents and young adults in managing the stress associated with cancer survivorship. Participants will engage in the PRISM program, which includes six sessions of resilience education delivered through a mobile app, text, or video coaching. The study employs a randomized design where participants may be assigned to different intervention methods to evaluate their effectiveness. The research will last up to six months and involves screening and questionnaires to assess participant eligibility and progress.

Who should consider this trial

Good fit: Ideal candidates are adolescents and young adults aged 12 to 25 who have completed their main cancer-directed therapy.

Not a fit: Patients who are not fluent in English or Spanish, or those who are unable to participate cognitively, may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could significantly enhance the ability of young cancer survivors to cope with stress and improve their overall mental health.

How similar studies have performed: Previous studies have shown promise in using mobile and digital interventions for stress management in similar populations, indicating a potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Participants that have completed their main cancer-directed therapy at one of the study sites affiliated centers who meet all the eligibility criteria will be eligible for participation in this study.

Inclusion Criteria:

* All genders ≥ 12 and ≤ 25 years of age at baseline
* Participant is able to speak English or Spanish language (for PRISM sessions)
* Participant is able to read English or Spanish language (for completion of surveys)
* Participant is cognitively able to participate in PRISM sessions and complete written questionnaires and surveys, as judged by the site investigator

Where this trial is running

Boston, Massachusetts and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stress, Anxiety, Stress Management

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.