Helping caregivers of people with dementia manage depression

Supporting Family Caregivers of People With Dementia and Identifying an Effective Adaptive Intervention to Reduce Their Depressive Symptoms: a Sequential Multiple Assignment Randomized Trial

Not applicable Interventional The Hong Kong Polytechnic University · NCT05634317

This study is testing a new program using smartphone tools to help family caregivers of people with dementia manage their depression and feel better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment136 (estimated)
Ages18 Years and up
SexAll
SponsorThe Hong Kong Polytechnic University Academic / other
Locations1 site (Hong Kong)
Trial IDNCT05634317 on ClinicalTrials.gov

What this trial studies

This study aims to support family caregivers of individuals with dementia by implementing a two-stage adaptive intervention that includes smartphone-delivered behavioral activation and mindfulness practices. A total of 272 caregivers experiencing mild to moderate depressive symptoms will be recruited and assessed at multiple time points to evaluate the effectiveness of these interventions. The study utilizes a sequential multiple randomized trial (SMART) design to adapt interventions based on individual responses, thereby optimizing care for caregivers. The findings will contribute to community capacity-building efforts and improve mental health outcomes for caregivers.

Who should consider this trial

Good fit: Ideal candidates for this study are family caregivers aged 18 or older who provide care for individuals with a confirmed diagnosis of dementia and exhibit mild to moderate depressive symptoms.

Not a fit: Patients who have participated in structured mind-body interventions or have acute psychiatric conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly reduce depressive symptoms in caregivers, enhancing their overall well-being and ability to provide care.

How similar studies have performed: Similar studies have shown promise in using adaptive interventions for mental health support, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. aged 18 or above
2. FC of an individual with a confirmed medical diagnosis of any type of dementia who has been residing in the community;
3. having been providing care for at least 3 months prior to recruitment
4. the presence of mild-to- moderate depressive symptoms (Patient Health Questionnaire-9 (PHQ-9) score 5 to 14).

Exclusion Criteria:

1. having participated in any structured mind-body intervention, cognitive therapy, or structured psychosocial intervention 6 months prior to recruitment
2. having acute psychiatric and medical comorbidities that are potentially life- threatening or would limit the caregivers' participation or adherence (e.g., suicidal ideation, acute psychosis).

Where this trial is running

Hong Kong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.