Heart Coherence Training for Patients with Vascular Ehlers-Danlos Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of an 8-week virtual Heartmath® intervention designed to help patients with Vascular Ehlers-Danlos Syndrome (VEDS) manage stress and anxiety through biofeedback techniques. VEDS is a severe condition caused by mutations in the COL3A1 gene, leading to significant health risks and mental health challenges. The intervention aims to improve heart rate variability and overall quality of life by teaching patients non-pharmacological strategies to regulate their autonomic nervous system. Participants will be monitored for changes in stress levels, anxiety, and physiological responses throughout the program.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants must be diagnosed with Vascular Ehlers-Danlos Syndrome verified by a mutation of the COL3A1 gene
* Ages 12-45 year at the time of enrollment
* Access to a smartphone as well as an additional device with camera and microphone
* Stable internet access
* English speaking

Exclusion Criteria:

* Non-English speakers
* Any conditions or developmental delays limiting the ability to utilize technology or follow directions.

Where it's running

• Texas Children's Hospital
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Shaine A Morris, MD, MPH — Baylor College of Medicine
• Study coordinator: Shaine A Morris, MD, MPH
• Email: shainem@bcm.edu
• Phone: 832-826-5692

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Comparing Celiprolol to Placebo for Vascular Ehlers-Danlos Syndrome

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• Registry for hereditary cardiovascular diseases in Brazil

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• Registry for Ehlers-Danlos Syndrome

  This study is creating a registry to gather information from people with Ehlers-Danlos Syndrome to help researchers learn more about the condition and improve care for patients.

  Recruiting Istituto Ortopedico Rizzoli · Bologna, Emilia-Romagna · NCT04133272

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.