Health follow-up for children born after assisted reproductive techniques

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project will analyze clinical and anamnestic data from about 300 children born after advanced ART methods in Kazakhstan. Investigators will combine a retrospective review of perinatal and parental medication history with in-person assessments of anthropometrics, somatic health, basic neurological screening, and targeted urogenital examinations. Male children in the ICSI subgroup will have reproductive hormones (inhibin B, AMH) measured to characterize endocrine profiles. Results will be used to inform management principles and referral pathways tailored to children conceived by ART.

Why it matters

Who can join: the full rules

Inclusion Criteria:

For children:

* Born as a result of an ART program (IVF, ICSI, FET, or Fresh-ET).
* Age at the time of assessment: from birth up to 36 months.
* Availability of complete perinatal and medical documentation, including ART cycle characteristics and neonatal outcomes.
* Informed consent provided by parents or legal guardians for participation in the study and for biological sample collection (where applicable).

For mothers:

* History of pregnancy achieved through ART within the territory of Kazakhstan.
* Availability of data on pharmacological treatment before and during pregnancy (e.g., hormonal therapy, antithyroid drugs, vitamins, micronutrients).
* Willingness to provide anamnestic and perinatal information, and consent for access to medical records.

For fathers (in ICSI subgroup):

* Documented infertility factor necessitating ICSI.
* Agreement to provide relevant medical history and participate in comparative analyses (e.g., endocrine or reproductive parameters of father-son pairs).

Where it's running

• Международный клинический центр репродуктологии Persona
  Almaty, Kazakhstan Recruiting

Study contacts

• Study coordinator: Sevara Ilmuratova, PhD
• Email: ilmuratova.s@gmail.com
• Phone: +77778017305

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.