Head‑up, device‑assisted controlled elevation CPR for out‑of‑hospital cardiac arrest

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational registry collecting de‑identified data from EMS systems in the US and Europe that have implemented a head‑up CPR protocol combined with an impedance threshold device and either active compression‑decompression or automated mechanical compression. Participating systems submit patient demographics, detailed arrest care information, and outcomes from before and after implementation of the head‑up bundle, with a current focus on cases where the device combination was applied rapidly. All devices used in the registry have received FDA 510(k) clearance. The registry aggregates real‑world outcomes to monitor usage patterns and clinical results across diverse EMS settings.

Why it matters

Who can join: the full rules

Inclusion Criteria

1. Patient is at least 18 years of age
2. Patient is in active cardiac arrest, as defined by presence of either ventricular fibrillation or ventricular tachycardia, or pulseless electrical activity, or asystole at time of enrollment.
3. Patient receives either a) active-compression decompression cardiopulmonary resuscitation b) automated suction-cup based CPR with an impedance threshold device (ITD) c) manual CPR with an ITD
4. Subject receives device assisted controlled elevation of the head and thorax.

Exclusion Criteria

1\. Prisoners

Where it's running

• Hennepin Healthcare Research Institute
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Johanna C Moore, MD, MS — Hennepin Healthcare Research Institute
• Study coordinator: Johanna C Moore, MD, MS
• Email: johanna.moore@hcmed.org
• Phone: 612 873 4908

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.