Clinical trial No longer in our active list Interventional Ages 18 and up

Harmonica playing to improve lung function in COPD patients

Official title: The Effectiveness of Harmonica Playing in Improving Lung Function Among In-home Patients With Chronic Obstructive Pulmonary Disease

Run by The First Affiliated Hospital of Guangzhou Medical University · NCT05995847 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing if playing the harmonica can help people with COPD breathe better and improve their overall well-being compared to just regular care.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment248 (estimated)
SponsorThe First Affiliated Hospital of Guangzhou Medical University
Academic / other
Locations2 sites (Guangzhou, Guangdong and 1 other locations)
Trial IDNCT05995847 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals clinically diagnosed with COPD who meet the inclusion criteria.

Probably not a fit

Patients with recent COPD exacerbations, severe comorbidities, or cognitive disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of harmonica playing as a form of pulmonary rehabilitation for patients with chronic obstructive pulmonary disease (COPD). It compares a group receiving harmonica training combined with basic pulmonary rehabilitation care to a control group receiving only basic care. The study aims to assess improvements in lung function, self-efficacy, quality of life, compliance with training, and emotional distress among participants. By addressing the limitations of previous studies, this research seeks to provide robust evidence on the benefits of harmonica playing for COPD patients.

Why it matters

Potential benefit: If successful, this approach could enhance lung function and overall quality of life for COPD patients.

How similar studies have gone: While previous studies on harmonica playing have been limited, this approach is novel and aims to provide more comprehensive evidence of its effectiveness.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

● Clinical diagnosis of COPD.

Exclusion Criteria:

* Individuals with a history of COPD exacerbation within the last 6 weeks. An exacerbation is defined as a deterioration in at least two respiratory symptoms that necessitate hospitalization.
* Individuals with comorbidities that affect physical activity, such as severe cardiac or neurological disorders, cancer, or musculoskeletal problems.
* Individuals with cognitive disorders.
* Individuals unable to speak or understand spoken/written Chinese.
* Individuals who have participated in pulmonary rehabilitation (or any other structured, disease-related physical training) within the previous 6 months.
* Individuals who have played the harmonica, or other similar instrument, regularly in the previous 6 months.

Where it's running

  • The First Affiliated Hospital of Guangzhou Medical University
    Guangzhou, Guangdong, China
    Recruiting
  • The first affiliated hospital of Guangzhou Medical Univeristy
    Guangzhou, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.