Hand massage to relieve itching in people on hemodialysis

Effect of Hand Massage on Chronic Kidney Disease Associated Pruritus in Patients Receiving Hemodialysis: a Mixed Methods Study

Not applicable Interventional University of Applied Sciences of Western Switzerland · NCT07312916

This project will try regular hand massage to see if it reduces itching and improves sleep and quality of life for adults on hemodialysis with CKD-associated pruritus.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment54 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Applied Sciences of Western Switzerland Academic / other
Locations4 sites (Lausanne, Canton of Vaud and 3 other locations)
Trial IDNCT07312916 on ClinicalTrials.gov

What this trial studies

This mixed-methods randomized trial will assign 54 adults on hemodialysis with CKD-associated pruritus to either nurse-delivered hand massage or a verbal-attention control over three months. Quantitative outcomes (numeric rating scale, 5D Itch Scale, and KDQOL-SF v1.2) will be collected at baseline, one month, and three months. Twelve participants who receive the hand massage will take part in qualitative interviews to describe their experiences. The intervention is non-invasive and low-risk and the trial will explore both symptom change and possible mechanisms such as autonomic or neuropathic effects.

Who should consider this trial

Good fit: Adults (≥18) on hemodialysis for at least three months who speak French, report CKD-associated pruritus by VAS, and can give informed consent are eligible.

Not a fit: People with cognitive impairment, those who begin anti-pruritic medications after enrollment, or those who do not have CKD-aP or cannot attend the participating centers are unlikely to receive benefit from this intervention.

Why it matters

Potential benefit: If successful, hand massage could provide a safe, non-drug option to reduce itching and improve sleep and quality of life for people on hemodialysis.

How similar studies have performed: A few small short-term massage studies reported symptom improvement measured 48 hours after intervention, but longer-term randomized evidence is limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults ≥18 years
* on hemodialysis ≥ three months
* able to communicate in French
* diagnosed with CKD-aP based on VAS
* signed informed consent

Exclusion Criteria:

* Participants with cognitive impairment -
* participants who have been prescribed CKD-aP medications after enrollment in study.

Where this trial is running

Lausanne, Canton of Vaud and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Kidney Disease Associated Pruritus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.