Guiding blood flow management during major abdominal surgery using urethral perfusion index

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot trial aims to evaluate whether maintaining a specific urethral perfusion index during major abdominal surgery can improve tissue perfusion compared to standard care. The study will monitor urethral perfusion in patients undergoing elective surgeries lasting at least 120 minutes and will assess the correlation between urethral perfusion index and other vital signs. Additionally, it will explore the relationship between urethral and peripheral perfusion indices. The trial is conducted at a single center, focusing on a specific patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* at least 45 years old
* scheduled for elective major abdominal surgery (involving visceral organs with an expected duration of at least 120 minutes)
* indication for an arterial catheter
* indication for an urinary catheter

Exclusion Criteria:

* Pregnancy
* Planned surgery: nephrectomy, liver or kidney transplantation surgery
* Patients who previously had surgery on the urethra or bladder
* Patients without clinical indication for continuous blood pressure monitoring with an intraarterial catheter

Where it's running

• University Medical Center Hamburg-Eppendorf
  Hamburg, Germany Recruiting
• University Medical Center Hamburg-Eppendorf
  Hamburg, Germany Not yet recruiting

Study contacts

• Principal investigator: Bernd Saugel, MD — University Medical Center Hamburg Eppendorf, Hamburg, Germany and OUTCOMES RESEARCH Consortium®, Houston, Texas, USA
• Study coordinator: Bernd Saugel, MD
• Email: b.saugel@uke.de
• Phone: +49741052415

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• How external factors affect 2D-NIRS tissue oxygenation measurements in healthy volunteers

  This study tests how things like temperature, activity, caffeine, and nicotine influence 2D-NIRS measurements of tissue oxygenation in healthy adults.

  Recruiting Heinrich-Heine University, Duesseldorf · Düsseldorf · NCT07854431

• How giving fluids changes tiny blood flow in critically ill patients with venous congestion.

  This project will see if giving a fluid bolus makes tiny blood flow worse in ICU patients who have venous congestion compared with similar patients without congestion.

  Recruiting Università Politecnica delle Marche · Ancona, Italy · NCT07499401

• COMA.NET: Targeted treatment for coronary microcirculation problems

  This trial will test whether tailoring medicines based on intracoronary microvascular testing improves quality of life for people with ischemia but no large artery blockages.

  Recruiting Medical University of Bialystok · Bialystok · NCT07498231

• Using bedside microcirculation checks to guide early fluids in sepsis

  This study will test whether nurses measuring peripheral perfusion and skin mottling in adults with suspected sepsis in the emergency department and prompting an early 500 mL fluid bolus when perfusion looks poor can reduce short-term worsening.

  Recruiting at 6 sites University Hospital, Limoges · Brivé and 5 other locations · NCT06910891

• Evaluating muscle weakness in ICU survivors through exercise testing

  This study is trying to see how problems with blood flow after being in the ICU affect the strength and exercise ability of patients who survived serious illnesses like sepsis and shock.

  Recruiting at 2 sites University of Manitoba · Winnipeg, Manitoba and 1 other locations · NCT06193980

• Effects of fluid infusion rates on blood circulation during surgery

  This study tests how different rates of fluid given during surgery can improve blood flow and oxygen delivery to tissues for patients undergoing elective surgeries with little blood loss.

  Recruiting University Hospital Hradec Kralove · Hradec Králové · NCT05606536

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.