Guided treatment of lymph nodes in breast cancer after chemotherapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of using nanocarbon tracing to guide axillary lymph node treatment in patients with early breast cancer who have undergone neoadjuvant chemotherapy. A total of 100 patients diagnosed with stage N2 or N3 breast cancer will be recruited and treated at Liaoning Oncology Hospital. The study will assess the accuracy of sentinel lymph node biopsy (SLNB) following chemotherapy, aiming to reduce the false negative rate associated with conventional methods. Participants will receive ultrasound-guided injections of nanocarbon into the largest metastatic lymph node, followed by surgical evaluation within four weeks after completing chemotherapy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* invasive breast cancer confirmed by biopsy and histology;
* based on prone CT scan and Doppler ultrasound, axillary stage cN2-3;
* agree and meet the requirements for NAC;
* meet surgical requirements and agree to undergo surgery after NAC;
* the regime of NAC follows the NCCN recommendations.

Exclusion Criteria:

• previous history of breast cancer or other malignant tumors.

Where it's running

• Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute
  Shenyang, Liaoning, China Recruiting
• Jianyi Li
  Shenyang, Liaoning, China Recruiting

Study contacts

• Principal investigator: Jianyi Jianyi, Master — Cancer Hospital of China Medical University, Liaoning Cancer Hospital
• Study coordinator: Jianyi Li, Master
• Email: sjbreast@yeah.net
• Phone: 8618940257177

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.