Growth-plate behavior during and after temporary hemi‑epiphysiodesis and epiphysiodesis using RSA
Official title: Behaviour of the Growth Plate in Patients Operated With Either Permanent or Temporary Hemi-epiphysiodesis or Epiphysiodesis Through by the Use of Radiostereometric Analysis (RSA)
Run by Oslo University Hospital · NCT04235517 · Data updated 2026-11-12
This project will use radiostereometric analysis (RSA) with tiny implanted markers to test whether surgeons can precisely track growth of the growth plate in children treated for limb‑length differences or angular deformities.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 3 Years to 16 Years |
| Sex | All |
| Enrollment | 10 (estimated) |
| Sponsor | Oslo University Hospital Academic / other |
| Locations | 1 site (Oslo) |
| Status | Recruiting |
| Started | January 2017 |
| Main results expected | January 2027 |
| Study ends | January 2027 |
| Registry record updated | September 4, 2025 |
| Trial ID | NCT04235517 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children with idiopathic lower‑limb angular deformities or limb‑length discrepancy who are planned for temporary hemi‑epiphysiodesis, epiphysiodesis, or guided growth and who do not have a pathological physis.
✕Probably not a fit
Children with a pathological physis, those not undergoing the listed surgical procedures, or adults are unlikely to benefit from this specific approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
During surgery small tantalum beads are placed on either side of the growth plate, and follow-up RSA imaging is used to measure three‑dimensional growth with microscopic accuracy. The study follows children treated with temporary hemi‑epiphysiodesis, epiphysiodesis, or guided‑growth (tension band plating) for limb‑length discrepancy or idiopathic axial deviations. Researchers aim to detect asymmetric growth after the procedures and to define the optimal timing for implant removal. The design is observational and conducted at the orthopedic department of Oslo University Hospital, Rikshospitalet.
Why it matters
Potential benefit: If successful, the technique could help surgeons time implant removal more precisely and improve correction of limb‑length differences and angular deformities.
How similar studies have gone: Radiostereometric analysis is a well‑established precise method in orthopedics, but applying it specifically to guide timing of epiphysiodesis and guided‑growth implant removal is relatively novel with limited prior data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children with idiopathic axial deviations in the lower extremities * Children with limb length discrepancys where timing of epiphysiodesis is difficult because of a big discrepancy in skeletal age and chronological age Exclusion Criteria: * Children with axial deviations and pathological physis
Where it's running
-
The Ortopedic dep at Oslo Unversity Hospital, Rikshospitalet
Oslo, Norway Recruiting
Study contacts
- Study coordinator: Anne B Breen, MD
- Email: anneb3@ous-hf.no
- Phone: 92226905
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.