Growth-plate behavior during and after temporary hemi‑epiphysiodesis and epiphysiodesis using RSA
Behaviour of the Growth Plate in Patients Operated With Either Permanent or Temporary Hemi-epiphysiodesis or Epiphysiodesis Through by the Use of Radiostereometric Analysis (RSA)
This project will use radiostereometric analysis (RSA) with tiny implanted markers to test whether surgeons can precisely track growth of the growth plate in children treated for limb‑length differences or angular deformities.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10 (estimated) |
| Ages | 3 Years to 16 Years |
| Sex | All |
| Sponsor | Oslo University Hospital Academic / other |
| Locations | 1 site (Oslo) |
| Trial ID | NCT04235517 on ClinicalTrials.gov |
What this trial studies
During surgery small tantalum beads are placed on either side of the growth plate, and follow-up RSA imaging is used to measure three‑dimensional growth with microscopic accuracy. The study follows children treated with temporary hemi‑epiphysiodesis, epiphysiodesis, or guided‑growth (tension band plating) for limb‑length discrepancy or idiopathic axial deviations. Researchers aim to detect asymmetric growth after the procedures and to define the optimal timing for implant removal. The design is observational and conducted at the orthopedic department of Oslo University Hospital, Rikshospitalet.
Who should consider this trial
Good fit: Children with idiopathic lower‑limb angular deformities or limb‑length discrepancy who are planned for temporary hemi‑epiphysiodesis, epiphysiodesis, or guided growth and who do not have a pathological physis.
Not a fit: Children with a pathological physis, those not undergoing the listed surgical procedures, or adults are unlikely to benefit from this specific approach.
Why it matters
Potential benefit: If successful, the technique could help surgeons time implant removal more precisely and improve correction of limb‑length differences and angular deformities.
How similar studies have performed: Radiostereometric analysis is a well‑established precise method in orthopedics, but applying it specifically to guide timing of epiphysiodesis and guided‑growth implant removal is relatively novel with limited prior data.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children with idiopathic axial deviations in the lower extremities * Children with limb length discrepancys where timing of epiphysiodesis is difficult because of a big discrepancy in skeletal age and chronological age Exclusion Criteria: * Children with axial deviations and pathological physis
Where this trial is running
Oslo
- The Ortopedic dep at Oslo Unversity Hospital, Rikshospitalet — Oslo, Norway (Recruiting)
Study contacts
- Study coordinator: Anne B Breen, MD
- Email: anneb3@ous-hf.no
- Phone: 92226905
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.