Group psychotherapy for adults with mild anxiety and depression

Pilot Randomized Controlled Trial of an Integrative Group Psychotherapy (Terebenin's Method) in Adults with Subclinical and Mild/Moderate Anxiety and Depression

Not applicable Interventional S.lab (Soloways) · NCT06863948

This study is testing a new group therapy method to see if it can help adults with mild anxiety and depression feel better compared to regular treatments.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorS.lab (Soloways) Academic / other
Locations1 site (Novosibirsk)
Trial IDNCT06863948 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of Terebenin's Method, an integrative group psychotherapy approach, for adults experiencing subclinical and mild to moderate anxiety and depression. The therapy combines elements from psychodrama, family systemic methods, Gestalt therapy, and body-oriented techniques to enhance treatment outcomes. Participants will attend weekly group sessions for eight weeks, with follow-up visits that include saliva sample collection to assess physiological responses. The study aims to determine if this integrative approach can provide better relief from symptoms compared to traditional therapies.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-60 with subclinical, mild, or moderate anxiety and depressive symptoms who are not currently on psychotropic medications.

Not a fit: Patients with severe psychiatric disorders or significant suicidal risk will not benefit from this study.

Why it matters

Potential benefit: If successful, this therapy could offer a novel and effective treatment option for individuals struggling with mild anxiety and depression.

How similar studies have performed: Previous studies have shown that integrative psychotherapeutic approaches can be effective, suggesting potential success for this novel method.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18-60.

  * Subclinical, mild, or moderate anxiety/depressive symptoms (screened via HADS, BDI-II, STAI).
  * No current psychotropic medication use or on a stable dose for ≥4 weeks with no planned changes.
  * Ability to attend weekly group sessions for 8 weeks + follow-up visits, including saliva sample collection.
  * Provision of written informed consent.

Exclusion Criteria:

* Severe psychiatric disorders (e.g., schizophrenia, bipolar disorder in a manic phase, major depression with psychotic features).

  * Significant suicidal risk requiring urgent intervention.
  * Severe somatic illness impeding participation.
  * Active substance use disorder unless in stable remission for \>6 months.
  * Ongoing psychotherapy that could confound results.
  * Inability to comply with saliva collection (e.g., shift work, severe sleep disturbances).

Where this trial is running

Novosibirsk

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AnxietyDepression - Major Depressive Disorderdeprssionanxietypsychotherapycortisol
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.