GRAPE model for gastric cancer screening
Clinical Evaluation of GRAPE Model for Gastric Cancer Screening
Zhejiang Cancer Hospital · NCT07067983
This project will test whether the GRAPE computer model can help detect gastric cancer in adults aged 18–80 who are having thoracoabdominal CT scans.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000000 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Zhejiang Cancer Hospital (other) |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT07067983 on ClinicalTrials.gov |
What this trial studies
This is a prospective observational study enrolling adults aged 18–80 who undergo thoracoabdominal CT at Zhejiang Cancer Hospital. The GRAPE algorithm will be applied to systematic CT screening results to identify findings suggestive of gastric cancer. Detection rates will be recorded across different disease stages and compared with subsequent clinical diagnoses or follow-up. The study excludes people with a prior confirmed gastric cancer diagnosis and those unable to provide informed consent.
Who should consider this trial
Good fit: Adults aged 18–80 who are undergoing thoracoabdominal CT at the study site and can give written informed consent are ideal candidates.
Not a fit: People already diagnosed with gastric cancer, those unable to communicate or provide informed consent, and those outside the 18–80 age range are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the GRAPE model could increase early detection of gastric cancer from routine CT scans and help direct timely diagnostic follow-up.
How similar studies have performed: AI and computer models applied to medical imaging have shown promise in other cancers, but using the GRAPE model specifically for gastric cancer screening is relatively novel and not yet widely validated.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged between 18 and 80 years * Individuals undergoing thoracoabdominal CT examination * Voluntarily participated in the study and provided written informed consent Exclusion Criteria: * Patients with confirmed diagnosis of gastric cancer * Individuals with severe intellectual disabilities or communication disorders
Where this trial is running
Hangzhou, Zhejiang
- Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital) — Hangzhou, Zhejiang, China (RECRUITING)
Study contacts
- Principal investigator: Xiangdong Cheng — Zhejiang Cancer Hospital
- Study coordinator: Xiangdong Cheng
- Email: chengxd@zjcc.org.cn
- Phone: 0086-571-881280
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gastric Cancer